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Non-randomized clinical trial is the clinical trial in which the series of consecutive patients receive a new treatment and those which respond (according to some of the pre-defined criterion) continue to receive it. Those patients who fail to respond receive an alternative, generally the conventional, treatment. The two set of groups are then compared on one or more results variables. One of the problems with such type of a procedure is that patients who respond might be healthier than those patients who do not respond, possibly resulting in an obvious but not real advantage of the treatment.
Introduction to Generalized Linear Models (GLM) We introduce the notion of GLM as an extension of the traditional normal-theory-based linear regression models. This will be very
The procedure in which initially the sample of subjects is selected for generating the auxillary information only, and then the second sample is selected in which the variable of i
Described by the leading proponent as 'the conscientious, explicit, and judicious uses of present best evidence in making the decisions about the care of individual patients, and
stationary time series
Locally weighted regression is the method of regression analysis in which the polynomials of degree one (linear) or two (quadratic) are used to approximate regression function in
A family of the probability distributions of the form given as here θ is the parameter and a, b, c, d are the known functions. It includes the gamma distribution, normal dis
The values assigned to factors for the individual sample units in a factor analysis. The most common approach is "regression method". When the factors are seen as the random variab
The graphical process most frequently used in the analysis of data from a two-by-two crossover design. For each of the subject the difference between the response variable values o
The probability distribution which is a linear function of the number of component probability distributions. This type of distributions is used to model the populations thought to
Matching is the method of making a study group and a comparison group comparable with respect to the extraneous factors. Generally used in the retrospective studies when selecting
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