Molecular response to thyroid hormones, Operation Management

Molecular Response to Thyroid Hormones during Metamorphosis

Thyroid hormones can cause obtainable tissues to break down or can remold the tissues to their adult function. The liver cells of the tadpole for instance are not destroyed and replaced during metamorphosis. In place of their structure is remodeled. This change is accompanied by dramatic raise in ribosomal and messenger RNA synthesis. The rate of protein synthesis also increases nearly 100 folds in four hours of thyroid hormone stimulation. Many of the new mRNAs are those that code for new functions of the liver. The main increase in protein synthesis appears to come from the transcription of new m-RNAs.

Carbamoylphosphate synthase (a urea cycle enzyme) is synthesized after the burst of RNA synthesis. Experiments have illustrated three types of molecular response to thyroid hormone. One set of genes increases its low level of transcription in reply to either natural or thyroxine induced metamorphosis. Another set of genes decreases its rate of transcription, whereas a third set of genes remains unaffected by thyroid hormones. Mori and Coworkers (1979) have illustrated that much of the increase in Carbamoylphosphate synthase can be attributed to increased transcription from the gene. So metamorphosis appears to some extent to be controlled at the transcriptional level. Other evidences also indicate the capability of thyroid glands to regulate gene activity at the level of transcription. This does not mean that transcription is the only level of gene regulation, operative during metamorphosis, but it is obviously an important one.

Posted Date: 1/30/2013 6:48:21 AM | Location : United States







Related Discussions:- Molecular response to thyroid hormones, Assignment Help, Ask Question on Molecular response to thyroid hormones, Get Answer, Expert's Help, Molecular response to thyroid hormones Discussions

Write discussion on Molecular response to thyroid hormones
Your posts are moderated
Related Questions
Imagine you are creating a marketing plan for a company that will sell kites. As you consider the marketing program, what types of strategy should you consider including in the pla

Making Better Business Decision: Do you provide the quizzes/exams questions for this book? **You didn't answer my questions a Yes or No would have been sufficient. Please answer th

What are the major considerations regarding logistics alliances, for: a) initiation? b) implementation? c) maintenance? d) termination?

Compile a list of consumption behaviours which you consider unethical. For each behaviour listed, explain why you view it as wrong

You are in charge of a project that is investigating the effects of gender differences on the reading scores of first, third, and fifth grades in three different school districts.

Tony taxpayer´s return has come up for audit by the Internal Revenue Service (IRS). He took some deductions this year for an office in his home. Amelio Auditor at the IRS has disal

State of nature decision S1 S2 S3 D1 250 750 500 D2 300 -250

Point  Rating Method In  selecting  a site  of location companies  have several  objectives, but  not  all are  of equal  importance. The relative weight a company assigns to

The decline in union membership has been mainly attributed to what four factors? Answer (1) Change in economy, employee involvement, human resources practices, and government regul

From the case study, determine what ideals, obligations, and effects must be considered in using psychological tests as pre-employment screens. Decide which the most important cons