Methods of gene transfer in transgenic animals, Biology

Methods of gene transfer

The technology employed for introduction of transgenes into a livestock population may produce consequences specific to the method. Once introduced, transgenic animals will become subject to the traditional selection criteria of livestock producers and the market forces for the gene products involved. A transgene will likely be expanded into the breeding population so long as the associated trait remains desirable in production systems and the marketplace. By use of marker-assisted selection, a few transgenes could be selectively incorporated into or eliminated from an otherwise diverse breeding population without great difficulty. The method resulting in Polly is seen as a major improvement as compared to the technology of the early nineties that led to the first transgenic bovine creature, carrying the human lactoferrin gene (lactoferrin is an important component in breast milk). At that time, genes were injected into newly fertilized eggs, and only in rather infrequent cases did the gene stably integrate and lead to a transformed animal.

Although transgenic mice were produced three decade ago, the mouse is still the animal of choice and used as model system for most of the experiment.  However, currently pigs are used for most experiments because of its potential transgenic frequency.  Following are some of the gene transfer methods carried out in animals.

  1. Retroviral method
  2. Microinjection Method
  3. Nuclear transfer method

 

Posted Date: 9/18/2012 7:49:13 AM | Location : United States







Related Discussions:- Methods of gene transfer in transgenic animals, Assignment Help, Ask Question on Methods of gene transfer in transgenic animals, Get Answer, Expert's Help, Methods of gene transfer in transgenic animals Discussions

Write discussion on Methods of gene transfer in transgenic animals
Your posts are moderated
Related Questions
What is intracellular digestion? Intracellular digestion, or cellular digestion, is the breaking in the interior of the cell of big molecules coming from outside or even from i

Explain the Sex Composition of the Population? Sex composition of human population is one of the basic demographic characteristics, which is extremely vital for any meaningful


Explain a review of Eating Disorder? If you talk to a group of young boys and girls in an informal setting about their physical appearance, you will find that a majority of the

Q. What are the lateral lines of fishes? The lateral lines of bony fishes are sense organs that extend along both sides of the animal body they make contact with the environmen

For many of the mammalian Hox genes, it has been possible to determine that some of them are more similar to one of the insect HOM-C genes than to the others. Describe an experimen

The human blood group, related to the MN system is controlled by two alleles, S and s. Three distinct phenotypes can be identified by mean of biochemical tests. Among 1000 Britishe

Q. What are respectively some remarkable functions of albumin, myosin, CD 4 , keratin, immunoglobulin, reverse transcriptase, hemoglobin and insulin? Myosin is a protein that w

What are the main human degenerative diseases? The main human degenerative diseases are separated into three groups: cardiovascular diseases, neoplastic diseases and degenerat

Q. What are some signs and symptoms found in patients with hypothyroidism? In hypothyroidism the production and secretion of T3 and T4 are impaired. Since these thyroid hormone