Methods of gene transfer in transgenic animals, Biology

Methods of gene transfer

The technology employed for introduction of transgenes into a livestock population may produce consequences specific to the method. Once introduced, transgenic animals will become subject to the traditional selection criteria of livestock producers and the market forces for the gene products involved. A transgene will likely be expanded into the breeding population so long as the associated trait remains desirable in production systems and the marketplace. By use of marker-assisted selection, a few transgenes could be selectively incorporated into or eliminated from an otherwise diverse breeding population without great difficulty. The method resulting in Polly is seen as a major improvement as compared to the technology of the early nineties that led to the first transgenic bovine creature, carrying the human lactoferrin gene (lactoferrin is an important component in breast milk). At that time, genes were injected into newly fertilized eggs, and only in rather infrequent cases did the gene stably integrate and lead to a transformed animal.

Although transgenic mice were produced three decade ago, the mouse is still the animal of choice and used as model system for most of the experiment.  However, currently pigs are used for most experiments because of its potential transgenic frequency.  Following are some of the gene transfer methods carried out in animals.

  1. Retroviral method
  2. Microinjection Method
  3. Nuclear transfer method

 

Posted Date: 9/18/2012 7:49:13 AM | Location : United States







Related Discussions:- Methods of gene transfer in transgenic animals, Assignment Help, Ask Question on Methods of gene transfer in transgenic animals, Get Answer, Expert's Help, Methods of gene transfer in transgenic animals Discussions

Write discussion on Methods of gene transfer in transgenic animals
Your posts are moderated
Related Questions
Q. Explain Culture Characteristics of Molds? The gross appearance of a mold growing on a food often is sufficient to indicate its class or order. Some molds are loose and fluff


please help me with the general characteristics of the following classes:1.mammalia,2.ostichthyes,3.cyclostomata,4chondrichthyes,5.amphibia,6.reptilia

Describe the mechanisms and genetic regulations that underpin how two cells such as cardiomyocyte and a motor neuron have identical gnomes, yet are functionally and structurally di

Making leaf collections Collect young leaves of as many varieties of plants as possible. Place various layers of news- paper or blotting paper on a firm, smooth board. Next org

What are the major respective constituents of cell walls in bacteria, protists, fungi and plants? Ans) In bacteria cell wall is made of peptidoglycans; between protists algae ha

Phylogenetic or Cladistic Classification Phylogeny plays a great role in classification. It is the  appropriate theoretical background for taxonomy and is quite essential in exp

make assignment multiple alleles

57. While planning for an artificial hybridisation programme involving dioecious plants, which of the following steps will be irrelevant A usting of pollen on stigma B Collection

what is the technical term used for the animals that eat yellow grass?