Mechanism of blood coagulation, Biology

GENERAL MECHANISM OF BLOOD COAGULATION -

All researchers agree that blood clotting is a cascade mechanism and involves three essential steps - (a) Formation of prothrombin activator. It is formed in two ways :

Extrinsic pathway -

 

359_extrinsic pathway of blood coagulation.png

Intrinsic pathway

 

781_intrinsic pathway of blood coagulation.png

(b) Conversion of prothrombin into thrombin -

1273_blood coagulation.png

(c) Conversion of fibrinogen into fibrin -

                            Thrombin

Fibrinogen                                                         Fibrin Threads (insoluble) 

(soluble)

Fibrin threads form a meshwork which traps blood cells and platelets to form a clot so the process is called blood clotting. Within a few minutes, the clot begins to contract and a pale coloured fluid called serum is discharged. This is called clot-retraction.

Posted Date: 10/1/2012 3:34:15 AM | Location : United States







Related Discussions:- Mechanism of blood coagulation, Assignment Help, Ask Question on Mechanism of blood coagulation, Get Answer, Expert's Help, Mechanism of blood coagulation Discussions

Write discussion on Mechanism of blood coagulation
Your posts are moderated
Related Questions
Coxal Glands There is a pair of coxal glands, in almost all the segments in Onychophora (Peripatus). Developmentally; in every segment a hollow follicle or somite arises and i

Q. What do you undersand by pollution? The Pollution is the contamination of an ecosystem by factors that are harmful for the equilibrium of its abiotic or biotic constituents.

Feeding Mechanisms of Animals All animals have evolved successful methods for extracting their required nutrition from the environment. Thus we find a diversity of feeding mec

Caseous lymphadenitis Caseous lymphadenitis is a chronic disease of sheep and goats. It is characterized by abscess formation in lymph nodes and sometimes in lungs and other organ

Asymptomatic patient: The current opinion is that in asymptomatic patients with left ventricular dysfunction and severe MR surgery should not be delayed. The echo cardiographic a

Air Microbes

Explain the Vitamin K dependent proteins? The four vitamin K-dependent procoagulants (factor II or prothrombin, and factors VII, IX, and X), about which we studied above, are s

Q. Explain about Rheumatic Heart Disease? Rheumatic Heart Disease (RHD) is a very common cause of cardiovascular disorder in children and adolescents in India. This disease inv

Q. How do nucleotides of mRNA chains encode information for the formation of the amino acids sequences of a protein? There are only four types of nitrogen- containing bases tha

Physiognomy and Pattern Physiognomy is the general appearance of vegetation as determined by the growth, form of dominant species. It may be considered a synthetic character