Illustrate the stages of contact osteogenesis, Biology

Assignment Help:

Stages of Contact Osteogenesis

Osteoconduction: This is the first and the most important healing phase and relies on the recruitment and migration of osteogenic cells to the implant surface, through the residue of peri-implant blood clot. Fibrin attaches to the surface of the implant. Osteogenic cells bind to the fibrin. The firm adhesion of this fibrin network to the surface is necessary to prevent disruption of the fibrils from the surface during contraction of the blood clot, thus maintaining continuous contact guidance for the osteoblast migrating to the surface. The 3- D surface morphology determines the degree of cell attachment, quantity and time.

De novo bone formation:This is the second healing phase which results in a mineralized interfacial matrix equivalent to that seen in the cement line in the natural bone tissue.

It is the common factor linking normal tunneling remodeling and contact osteogenesis in which bone is formed for the first time at the appropriate site by the differentiating osteogenic cells.  These are cells which have migratory capacity but will still become osteoblast. Clearly an essential prerequisite of de novo bone formation is that bone cells must first get to either the old bone or implant surface respectively, before extracellular matrix synthesis is initiated.  At first the osteoblasts adhere to the  surface. Surrounded in a collagen matrix made of organic phosphate, they release phosphateions until the solubility of calcium phosphate has exceeded and crystallized to hydroxyapatite. Surface morphology as well as the existence of calcium and phosphate ions on the implant surface determines the speed of bone formation.

 


Related Discussions:- Illustrate the stages of contact osteogenesis

Relationship of ecology with other disciplines of biology, Relationship of ...

Relationship of Ecology with Other Disciplines of Biology In order to understand the scope and relevance of ecology let us consider its position in relation to other biological

Aeration, Aeration is the process on which water and air come into contact....

Aeration is the process on which water and air come into contact. It is carried out by spraying water in the form of spray or fountain over air. Aeration achieves the following obj

Protein prediction., I am trying to get help on the creation of a dataset f...

I am trying to get help on the creation of a dataset for protein prediction in matlab

Heart and lungs, what are the main functions of lungs and heart

what are the main functions of lungs and heart

Insulators - transgenic animals, Insulators Numerous experiments showed...

Insulators Numerous experiments showed that a transgene is generally poorly expressed when it contains a cDNA rather than the corresponding genomic DNA; when it is integrated a

Protostomes, differences between acoelomate,coelomate and pseudocoelomate

differences between acoelomate,coelomate and pseudocoelomate

Factors that effect birth weight and gestational duration, Define Factors t...

Define Factors that effect birth weight and gestational duration? A WHO review has identified 43 factors that influenced birth weight and gestational duration. They are grouped

Write short note on ames test, Question 1 Describe any two possible mec...

Question 1 Describe any two possible mechanisms of mutagenesis 2 Explain any five functions of Endoplasmic reticulum 3 Write short note on Ames test 4 Describe the structure an

Explain classification of lipids, Classification of lipids  A general c...

Classification of lipids  A general classification of lipids based on their structural components is presented in table. Such a classification, however, is possibly too rigid f

Explain trypsin, Trypsin Trypsin is secreted in the inactive  form  try...

Trypsin Trypsin is secreted in the inactive  form  trypsinor  -  which is converted into the active form  trypsin by  the enzyme enterokinase secrated by  the duodenal mucosa.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd