Horse diseases-borna disease, Biology

Borna disease

Borna disease is fatal neurological disease of horses and sheep caused by a virus (RNA) of the family Bornaviridae and the disease is characterized by sub acute meningoencephalitis and infiltration of mononuclear cells. The disease owes its name to the area around the town Borna in Saxony, Germany where a great number of horses died during an epidemic. The disease has not been reported in India

Clinical signs:
Incubation period is 4 weeks. The clinical picture in acute disease is dominated by symptoms due to meningitis and encephalomyelitis such as severe depression, permanent standing upright in unphysiological positions, ataxia, circular movements and running against obstacles, incoordination of movement, disturbed sensory functions, lethargy, paralysis and death.

Diagnosis: Indirect immunofluorescent assay is the most suitable test for detecting BDV specific antibodies in the serum and/or CSF. In histopathology, variable degree of encephalitis is observed in brain tissue of infected horses. Lymphocytic infiltrations are usually most common in the hippocampus, the brain stem and in parts of the cerebral cortex. Virus isolation from brain tissues of infected horses is not always successful. BDV can also be detected in brain tissue by nested PCR and viral antigen by a capture ELISA.

Posted Date: 9/18/2012 7:50:55 AM | Location : United States

Related Discussions:- Horse diseases-borna disease, Assignment Help, Ask Question on Horse diseases-borna disease, Get Answer, Expert's Help, Horse diseases-borna disease Discussions

Write discussion on Horse diseases-borna disease
Your posts are moderated
Related Questions
Explain Deteriorative changes in fats and oils The food products undergo changes in flavour due to the chemical changes occurring in fats and oils present in them. The causativ

3 main stages of bone formation, and explain the process of these 3 stages.

Phosphorus (P) - Macronutrients In soil, phosphorus occurs almost exclusively in the form of orthophosphate. Substantial amount of P is associated with the soil organic matter

CELLULOSE It is a linear polymer of b -D-glucose. It is the structural polysaccharide of plant cell walls, walls of some primitive fungi, some protists, and tunic of asci

Acute Complications of PTCA :  The incidence of complications after PTCA that require emergency surgery has reduced considerably in the present era. Introduction of stents, pe

What functions performed by Vitamin and Mineral for athletes? Vitamins and minerals perform the same essential functions for athletes and non-athletes alike. However, owing t

FORM S OF RIBOSOMES (1 )      Bound form - Attached to ER. Protein synthesis for secretion purpose occurs on bound ribosomes. (2 )      Free Ribosomes - Occur freely

What do enzymes do, and how? How is enzyme activity regulated in cells? How do ATPases u se ATP to make reactions go?

Explain Procedure for Detection of Metanil Yellow? Carry out the exercise following the steps enumerated herewith. 1. Suspend the food sample in water and shake vigorously.