Hormones of pancreas, Biology

HORMONES OF PANCREAS AND THEIR ROLE -

(i) Glucagon (Secreted by a-cells)

  • It stimulates the liver to convert stored glycogen into glucose.
  • Glucagon is controlled by feedback in accordance with the level of glucose in the blood. When the blood sugar rises, the secretion of glucagon is suppressed and when it drops, the secretion of glucagon is stimulated.

Target Cells. Glucagon acts on the cells of the liver and adipose tissue.

(ii) Insulin (Secreted by b-cells)

  • It was first prepared / found by Benting and Best.
  • A. F. sanger coined the term insulin & proposed the molecular structure of insulin (cow's insuline)
  • Human insulin was synthesized by "Tsan".
  • Insulin was the first protein that was artificially synthesized in laboratory and is crystallized.
  • One molecule of insulin is made up of 51 amino acids that has 2 chains - (i) a-chain. It is made up of 21 aminoacids.

(ii) b-chain. It is made up of 30 amino acids. Both the branches or chains are bind together with cross bonds of disulphide bonds.

(iii) Somatostatin (SS)

It regulates the secretion of insulin and glucagon.

Target Cells. Both somatostatin and pancreatic polypeptide act on the cells of the pancreas.

(iv) Pancreatic Polypeptide (PP).

It appears that pancreatic polypeptide inhibits the release of digestive' secretion of the pancreas.

Both somatostatin and pancreatic polypeptide are relatively newly discovered hormones of the pancreas, and both are still being studied.

Posted Date: 10/2/2012 7:03:07 AM | Location : United States







Related Discussions:- Hormones of pancreas, Assignment Help, Ask Question on Hormones of pancreas, Get Answer, Expert's Help, Hormones of pancreas Discussions

Write discussion on Hormones of pancreas
Your posts are moderated
Related Questions
Ornithophily - Cross-pollination In tropical areas, the birds dominate over insects as important pollinators. The most common among them are humming-birds, sun-birds and honey

What is cell cycle? Cell cycle, or mitotic cycle, is the time period that starts when the cell is formed and finishes when it is divided by mitosis making two daughter cells. T

Explain therapeutic diet planning All detailed dietary modifications  should be presented with choices,  clear guidelines, menu guidance and supporting  information  as  to  al

Was there molecular oxygen in the earth's primitive atmosphere? How has that molecule become abundant? The presence of the molecular oxygen in the primitive atmosphere was prob

GER M PLASM THEORY - It was proposed by Weismann. According to it, two types of cells are formed during embryonic development viz - Germ cell & Somatic cell. The germ ce

Applications :  The first operation conducted was ligation of a patent ductus arteriosus through a left thoracotomy. Same approach is used for repair of coarctation of the aorta,

Characteristics of Gametes Following are some general characteristics of gametes: 1. The female gametes are usually laden with food material, the yolk, while the male gamet

Diagnosis X-ray chest shows cardiomegaly.  ECG shows conduction defect, low voltage QRS, atrial and ventricular disrhythrnias.  Echocardiogram - decreased LV cont

EMBRYONI C MEMBRANES - Such animals are called amniota. Embronic membranes are of 4 types - (i) Yolk sac - It is formed below the embryo. It contains fluid (no yolk

Q. What are the cells with a delimited nucleus called and what are the major elements of the nucleus? Cells with delimited nucleus are known eukaryotic cells. Organisms compose