Hormones of pancreas, Biology


(i) Glucagon (Secreted by a-cells)

  • It stimulates the liver to convert stored glycogen into glucose.
  • Glucagon is controlled by feedback in accordance with the level of glucose in the blood. When the blood sugar rises, the secretion of glucagon is suppressed and when it drops, the secretion of glucagon is stimulated.

Target Cells. Glucagon acts on the cells of the liver and adipose tissue.

(ii) Insulin (Secreted by b-cells)

  • It was first prepared / found by Benting and Best.
  • A. F. sanger coined the term insulin & proposed the molecular structure of insulin (cow's insuline)
  • Human insulin was synthesized by "Tsan".
  • Insulin was the first protein that was artificially synthesized in laboratory and is crystallized.
  • One molecule of insulin is made up of 51 amino acids that has 2 chains - (i) a-chain. It is made up of 21 aminoacids.

(ii) b-chain. It is made up of 30 amino acids. Both the branches or chains are bind together with cross bonds of disulphide bonds.

(iii) Somatostatin (SS)

It regulates the secretion of insulin and glucagon.

Target Cells. Both somatostatin and pancreatic polypeptide act on the cells of the pancreas.

(iv) Pancreatic Polypeptide (PP).

It appears that pancreatic polypeptide inhibits the release of digestive' secretion of the pancreas.

Both somatostatin and pancreatic polypeptide are relatively newly discovered hormones of the pancreas, and both are still being studied.

Posted Date: 10/2/2012 7:03:07 AM | Location : United States

Related Discussions:- Hormones of pancreas, Assignment Help, Ask Question on Hormones of pancreas, Get Answer, Expert's Help, Hormones of pancreas Discussions

Write discussion on Hormones of pancreas
Your posts are moderated
Related Questions
Describe the Frequency of low-risk coronary patients? For many low-risk coronary patients, particularly those following myocardial revascularization procedures, rehabilitation

Why is drosophila a convenient animal for the study of linked genes? The fruit fly drosophila is suitable for the study of Genetics because it shows many distinct traits but on

In biology, a species is smallest and basic unit of classification. Each species is placed within a single genus. For example biological name of human being is homosapiens. Here ho

Q. Can high blood pressure causes the cardiovascular disease? Hypertension or high blood pressure: It is also one of the risk factors of cardiovascular disease and is frequentl

Q. What is the difference between disaccharides and monosaccharides? What are some examples of monosaccharides and of disaccharides that form them? Monosaccharides are simple m

Sickle cell anaemia in man is caused by a defective chain of haemoglobin. The abnormal haemoglobin known as MbS differs from natural haemoglobin (HhA) in one amino acid. A substitu

What is the difference between recessive allele and dominant allele? The Dominant allele is the allele that determines phenotypical features that manifest in heterozygous or ho

The part of human brain which is a significant relay station for the sensory impulses and also is the origin of many of the involuntary acts of eye such as narrowing of the pupil i

Q. What are the major cellular features of fungi? There are pluricellular and unicellular fungi. All fungi are heterotrophs and eukaryotes. Fungi have cells with cell wall m

Define Placental secretion of oestrogens During pregnancy? Placental secretion of oestrogens increase with progression of pregnancy. Oestrogens perform many functions. They sti