Goat-pox is common in occurrence, and its nature is similar to sheep pox. The incubation period varies from 5 to 10 days. The disease tends to attack male kids and ewes in milk. Initially there may be slight pyrexia, but in most outbreaks constitutional disturbances are not marked. The lesions, which are not big and widespread like sheep- pox, occur on the lips and oral mucosa, the teats and udder; and the affected parts are axilla, thighs, nose and mouth. In the females, udder may also be involved. The goat- pox virus affords partial protection in sheep against sheep-pox, and Kenyan strain of sheep-pox virus protects goats against the goat-pox.Inactivated and live attenuated vaccines developed by IVRI, Mukteswar with or without adjuvants, for protection against goat-pox are being evaluated.