Germ line gene therapy, Biology

Germ line gene therapy - This approach either targets to correct the totipotent cells within human conceptus or stimulate the genetic modifications within reproductive cells that is gametes (sperms or eggs) (Elias and Annas, N.D). It produces permanent and irreversible results which get transmitted to the future generations. A fertilized egg develops into an embryo from which all the cells of the body originate. Hence a correction of genetic errors introduced during the early stages of embryogenesis gets transmitted to every cell of the offspring. This approach is more effective in comparison to somatic gene therapy as it produces long lasting effects throughout the body (Henry, N.D). This approach is also used during creation of transgenic animals. The ultimate target of this approach is to eradicate certain genetic disorders from a particular family or population as a whole. As the effects of this therapy get deliberately passed to future generation unlike other medical interventions, the practical application of this therapy within human beings is under debate(Elias and Annas, N.D). People who stand against this therapy fear that it may alter the gene pool, lead to social dangers or increase the chances of possible clinical risks (Elias and Annas, N.D).


Posted Date: 8/9/2012 6:33:27 AM | Location : United States

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