Explain isobologram., Advanced Statistics

Isobologram is a diagram used to characterize the interactions among jointly administered drugs or the chemicals. The contour of the constant response (that is the isobole), which is compared to the 'line of additivity', that is the line connecting the single drug doses which yield the level of response related with that contour. The interaction is described as the synergistic, additive, or an antagonistic according to whether the isobole is below, or coincident with, or above the line. 

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