Explain epitope, Biology

Epitope: As related to the protein antigens, B-cell epitopes comprises the amino acid residues of the protein molecule in which interact directly through the noncovalent bonds with amino acid residues of the particular antibody molecule (complementarity determining the area). The average epitope probably includes about 15-20 contact amino acid residues, but one or two of these might be critical to the epitope's specificity and the avidity of the antibody-antigen reaction. B-cell epitopes might be either linear in nature or conformational in nature. T-cell epitopes represent small, processed peptides which bind to the MHC class I and II molecules on surface of T cells.

Posted Date: 8/3/2012 6:46:24 AM | Location : United States







Related Discussions:- Explain epitope, Assignment Help, Ask Question on Explain epitope, Get Answer, Expert's Help, Explain epitope Discussions

Write discussion on Explain epitope
Your posts are moderated
Related Questions
Where in the cell can ribosomes be found? What is the main biological function of ribosomes? Ans) Ribosomes can be found free in the cytoplasm, adhered to the outer side of the

Q What is the excretion? Excretion in Physiology is the procedure of elimination of metabolic wastes and other toxic substances from the body.

Highly active antiretroviral therapy (HAART) - The treatment of HIV infection requires combination therapy known as highly active antiretroviral therapy (HAART) along with inte

Spinal cord Spinal cord is a long and cylindrical structure. It passes through the vertebral column extending all along the dorsal surface of trunk. Vertebrae of the v

Parthenogenesis The development of egg to form an animal without fertilization is called as parthnogenesis. Parthenogenesis was discovered by Charles Bonnet in the egg of se

Lysosomes Lysosomes are small vesicles which are bounded by a single membrane & contain hydrolytic enzymes in the form of minute crystalline or semi crystalline granules of


Fate of Blastopore Cleavage results in the formation of a ball of cells called morula (resembling mulberry hence the name). A space appears in the morula changing it to a holl

Q. Investigations process of constrictive pericarditis? Electrocardiogram Low voltage complexes can occur. Left atrial enlargement may be seen. Atrial fibrillation occu

Q. What are the factors which influence the spoilage of meat? Can you list a few? Ans. Sure enough, you should be able to enumerate these having learnt about them earlier