Donor selection and kidney preservation, Biology

DONOR SELECTION & KIDNEY PRESERVATION -

A kidney donor should be free of hypertension, diabetes & melignancy.

Cardaveric kidney is obtained from brain death person. Kidney are removed as early as possible, flushed with special cooling solutions such as mannitol & stored in iced solution. Preserved kidney usually fucntion normaly if transplanted within 48 hrs.

RECIPIENT DONOR MATCHING -

Tested for 3 factors.

(i) Blood group                 (ii) Human leucocyte antigen (HLA)        (iii) Antibodies

On surface of leucocyte 6 antigen present (3 from father & 3 from mother).

Maximum matching is recommended.        

Small samples of blood of recipient & donor are mixed. If no reaction, then pateint will be able to accept kidney.

 

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Posted Date: 10/2/2012 5:43:17 AM | Location : United States







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