The ability to sequence DNA has led to a revolution in molecular biology.
a) Describe the principles of DNA sequencing.
b) A single sequencing reaction yields at best 1500 bases of good sequence data, yet the human genome is billions of base pairs long. Describe the ways in which laboratory and bioinformatics techniques can be combined to overcome this limitation allowing entire genomes to be sequenced.
c) Explain how laboratory and bioinformatics approaches can be used to analyse the functions of genes.