Definition of osseointegration in microscopic biology, Biology

Q. Definition of Osseointegration in microscopic biology?

From a view point of macro and microscopic biology and medicine. Osseointegration of a fixture in bone is defined as the loose apposition of new and reformed bone in congruence with the fixture, including surface irregularities, so that at light microscopic level, there is no interpositioned connective or fibrous tissue and that a direct structural and functional connection is established, capable of carrying normal physiological loads without excessive deformation and without initiating rejecting mechanism.

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