Chronic bronchitis, Biology

Chronic Bronchitis

Chronic Bronchitis is defined clinically as hypersecretion of mucus and recurrent episode of productive cough for a period of 3 months per year at least two consecutive years. 

Pathophysiology

First there is glandular hypertrophy. Mucous gland hypertrophy and hyperplasia from chronic irritations cause excessive mucus production. The excessive mucus and impaired ciliary movement associated with chronic bronchitis increase susceptibility to infection. As infection progress, the epithelial cells produce a mucopurulent exudates in the lumen or the disease may progress to ulceration and destruction of the bronchial wall. The peribronchial fibrosis and the presence of granulation tissue result in stenosis and airway obstruction.

Second the bronchial wall tissue changes, mucosal ocdema and excessive mucus production, all increase airway resistance in persons with chronic bronchitis. Excess mucus may also cause bronchospasm. 

Third the pathophysiologic changes may impair the ability of lungs to exchange 0, and CO, leading to ventilation-perfusion mismatching at the alveolar-capillary membrane. Obstructed airways may lead to atelectasis which further diminishes the surface are a available for respiration. Fourth the right ventricular decompensation or corpulmonale may result.

Posted Date: 11/2/2012 7:00:40 AM | Location : United States







Related Discussions:- Chronic bronchitis, Assignment Help, Ask Question on Chronic bronchitis, Get Answer, Expert's Help, Chronic bronchitis Discussions

Write discussion on Chronic bronchitis
Your posts are moderated
Related Questions
What are lichens? How do fungi participate in this ecological interaction? Lichens are produced by mutualist ecological interaction among fungi and algae or among fungi and cya

Transplantation - It is implanting of a living or preserved tissue or organ from one site to another side in the same individual or from one individual called donor to recip

Q. What are the nucleic acids? What is the historic origin of this name? RNA and DNA, the nucleic acids, are the molecules responsible for the hereditary information that comma

Osmotic and Ionic Regulation The  ammonotelism, ureotelism and uricotelism are the adaptations of the animals for the removal of toxic nitrogenous wastes and thereby maintain

Homeostasis Homeostasis may be defined as the maintenance of constancy in the internal environment of the organism. This is essential for maintenance of life. Without homeost

Besides the XY system are there other sex determination systems? A few animals have a sex determination system different from the XY system such as the X0 system is the sex det

What are the capillaries of the vascular system? Capillaries are small blood vessels that perform exchange of substances among the blood and the body tissues. Capillaries are n

Two chromosomes in a cell have identical length and centromere position yet are not homologous, what is different about them.


What is the Implant Placement The failure to place an implant in the correct location in the buccolingual plane, mesiodistal plane and the inciso cervical plane results in the