Choice of transgenic animal, Biology

Choice of transgenic animal

First and foremost is the selection of animal species in which gene of interest is to be transferred. Whatever is the goal of production of transgenic animal production, mice in which specific mutations have been deliberately introduced, have often served very useful models for studying human genetic diseases such as cystic fibrosis. In some cases, differences between mice and human mean that the effects of the introduced mutation are not the same as in the human genetic disease. Yet this model served the science in knowing, how a gene and its regulatory elements are working in an animal system, the impact of transgenes on health and productivity of the animal, and the level of recovery of recombinant protein including the workout cost of therapeutic protein to alter the strategies in the target farm animal species. When one talks about the choice of farm animal species, it is to be seen that what is the purpose of production of a transgenic animal and in which tissue one wants to get the recombinant protein likely to express itself? If the protein is secreted in milk, dairy animals like goats and cattle are preferred, while for xenotransplantation, pig and sheep are the ideal species.

Posted Date: 9/18/2012 7:40:36 AM | Location : United States







Related Discussions:- Choice of transgenic animal, Assignment Help, Ask Question on Choice of transgenic animal, Get Answer, Expert's Help, Choice of transgenic animal Discussions

Write discussion on Choice of transgenic animal
Your posts are moderated
Related Questions
Q. What do you mean by Primary Metabolites ? As the name indicates, primary metabolites are molecules involved in vital metabolic pathways. They are of universal occurrence and

Explain Lamivudine It is probably the best tolerated of the NRTIs and can be taken once or twice daily. An increase in viral load during treatment with a lamivudine-containing

Phenylketonuria is a severe form of mental disability caused by a homozygous recessive allele. The condition affects about 1 in 10,000 neborn Caucasians. Estimate the frequency of

What is Vacuoles A very conspicuous feature in most plant cells is the presence of one or more large vesicles called vacuoles which are separated from the rest of the cytoplasm

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Define Milk as a rich source of protein? A value of 3.5% protein is often considered as an average for milk. Milk protein has traditionally been divided into 2 classes - casein

Q. What is plutonium reprocessing? Why is it a big environmental issue? The Plutonium is the highly radioactive chemical element produced from uranium by nuclear plants. The Pl

Osler's nodes are small, tender subcutaneous nodules that develop in the pulp of the digits or occasionally more proximally in the fingers and persist for hours to several days. Th

What compound composes most of the cell membrane? How is this compound suited to the function of the membrane? Phospholipid composes most of the cell membrane. The hydrophob

Explain the Characteristics of Cancer? The important characteristics of cancer are excessive cellular multiplication, invasiveness and autonomy. The active process of invasion