Choice of transgenic animal, Biology

Choice of transgenic animal

First and foremost is the selection of animal species in which gene of interest is to be transferred. Whatever is the goal of production of transgenic animal production, mice in which specific mutations have been deliberately introduced, have often served very useful models for studying human genetic diseases such as cystic fibrosis. In some cases, differences between mice and human mean that the effects of the introduced mutation are not the same as in the human genetic disease. Yet this model served the science in knowing, how a gene and its regulatory elements are working in an animal system, the impact of transgenes on health and productivity of the animal, and the level of recovery of recombinant protein including the workout cost of therapeutic protein to alter the strategies in the target farm animal species. When one talks about the choice of farm animal species, it is to be seen that what is the purpose of production of a transgenic animal and in which tissue one wants to get the recombinant protein likely to express itself? If the protein is secreted in milk, dairy animals like goats and cattle are preferred, while for xenotransplantation, pig and sheep are the ideal species.

Posted Date: 9/18/2012 7:40:36 AM | Location : United States

Related Discussions:- Choice of transgenic animal, Assignment Help, Ask Question on Choice of transgenic animal, Get Answer, Expert's Help, Choice of transgenic animal Discussions

Write discussion on Choice of transgenic animal
Your posts are moderated
Related Questions
Q. Complications in Gastric ulcers? Peptic ulcers if not managed properly can result in serious consequences which can even be life threatening. The complications involved in

Enumerate different implant materials with their pros and cons Biomaterials fall into four categories: metal and metal alloys, ceramics (carbon included in this group) syntheti

Q. What is Diverticular Disease? A common disorder of the large bowel, diverticulosis, is an early stage of the disease. It can be identified in 15% of the people over the age

Q. Write the meaning of Hypoglycemia? Hypoglycemia is a Greek term: hypo -meaning less; glyc - means sweet; and emia - means "of the blood". It is a condition in which less th

Determine the Basic Seven Food Groups - Nutritions? These basic seven food groups are: 1) Cereals and cereal products 2) Pulses (also meat and meat products) 3) Milk and m

Open and Closed Type of Circulatory Systems There are two categories of circulatory system found in higher metazoans. In one type the original blastocoel carries on to be the

During which meiosis division does ploidy reduction occur? Does ploidy reduction occur in mitosis? In the cell division by meiosis ploidy reduction occurs in meiosis II. Initia

Food Applications of Carrageenan Carrageenan consists of a family of hydrocolloids, which have different properties and it has a wide variety of uses. Some examples of properti

Q. Etiological factor of malabsorption syndrome? The causes cited for malabsorption can be associated with a number of diseases. Many of these diseases you may not know presen

Explain the Absorption of Protein? Although single amino acids are liberated in the intestinal contents, there is insufficient power in the enzymes of the pancreatic juice to r