Bovine spongiform encephalopathy, Biology

Bovine spongiform encephalopathy

The bovine transmissible spongiform encephalopathy (BSE), known as 'mad cow disease'-first noticed in Great Britain in 1986, is similar to scrapie in sheep and Creustfeld Jacob syndrome (CJD) in man, chronic wasting disease of captive mule deer and rocky mountain elk and transmissible encephalopathies in mink. It has been reported from Northern Ireland, the Republic of Ireland, Oman, Switzerland, France, Germany and a few other European countries. There is no report of BSE in India so far although doubtful cases of CJD in human beings have been reported. The causative agent is structurally different from a virus in that it contains protein (PrP) which is a transformed naturally occurring protein constituent of neurons that is encoded by a single chromosomal gene and devoid of nucleic acid. This agent measures 30-50 nm and is extremely resistant to inactivation by heating, UV-irradiation and many chemicals. BSE is classified as Prion disease.


Epidemiology: The disease in cattle occurred as a result of feeding them with ruminant protein supplements in meat and bone-meal derived from scrapie-affected sheep.


Symptoms:
It is difficult to diagnose the disease on the basis of clinical signs since such signs are not quite spectacular. Histopathological and histochemical studies, electron microscopy and biochemical analysis for detection of prion protein are presently available for laboratory confirmation of the disease.Prevention, control and treatment: Identification and slaughtering of positive and suspected cases are the only means of control measures available at present

Posted Date: 9/18/2012 6:53:01 AM | Location : United States







Related Discussions:- Bovine spongiform encephalopathy, Assignment Help, Ask Question on Bovine spongiform encephalopathy, Get Answer, Expert's Help, Bovine spongiform encephalopathy Discussions

Write discussion on Bovine spongiform encephalopathy
Your posts are moderated
Related Questions
Explain Methodology Required for Osazone Test? Take about 250-300 mg of phenylhydrazine mixture in the 3 clean labelled 15 ml dry test tubes. Add 5 ml of the glucose, fructose

Chronic Mitral Regurgitation :  In chronic mitral regurgitation, the asymptomatic phase is much longer than in mitral stenosis. Onset of symptoms may also mean the onset of l

what year did virchow state where a cell exists there must have been a pre-existing cell

What are the typical vegetation and the typical fauna of the tropical forests? In the vegetation of the tropical forests broadleaf evergreen trees predominate. On the top of th

general characteristics of cynobacteria

Neurochemistry of Attention Different neurotransmitters systems are implicated in attention. Cholinergic, dopaminergic and serotonergic systems play major roles in neurochemica

We now understand that mutations that cause the inhibition of apoptosis are found in tumors. Because proliferation itself is not induced by the inhibition of apoptosis, explain how

What is Binary Fission in cell reproduction? Cell division takes place in prokaryotic cells by binary fission, also called prokaryotic fission. In prokaryotes, DNA is contained

Define Assessment of Chromium Status? No specific tests are currently available, which could help us to determine chromium status. Another reason being the chromium content of

Q. Explain Therapy for diarrhoea? The therapy for diarrhoea thus consists of: 1. Determining the status of dehydration 2. Fluid management * Oral Rehydration Therapy (