Bovine spongiform encephalopathy, Biology

Bovine spongiform encephalopathy

The bovine transmissible spongiform encephalopathy (BSE), known as 'mad cow disease'-first noticed in Great Britain in 1986, is similar to scrapie in sheep and Creustfeld Jacob syndrome (CJD) in man, chronic wasting disease of captive mule deer and rocky mountain elk and transmissible encephalopathies in mink. It has been reported from Northern Ireland, the Republic of Ireland, Oman, Switzerland, France, Germany and a few other European countries. There is no report of BSE in India so far although doubtful cases of CJD in human beings have been reported. The causative agent is structurally different from a virus in that it contains protein (PrP) which is a transformed naturally occurring protein constituent of neurons that is encoded by a single chromosomal gene and devoid of nucleic acid. This agent measures 30-50 nm and is extremely resistant to inactivation by heating, UV-irradiation and many chemicals. BSE is classified as Prion disease.


Epidemiology: The disease in cattle occurred as a result of feeding them with ruminant protein supplements in meat and bone-meal derived from scrapie-affected sheep.


Symptoms:
It is difficult to diagnose the disease on the basis of clinical signs since such signs are not quite spectacular. Histopathological and histochemical studies, electron microscopy and biochemical analysis for detection of prion protein are presently available for laboratory confirmation of the disease.Prevention, control and treatment: Identification and slaughtering of positive and suspected cases are the only means of control measures available at present

Posted Date: 9/18/2012 6:53:01 AM | Location : United States







Related Discussions:- Bovine spongiform encephalopathy, Assignment Help, Ask Question on Bovine spongiform encephalopathy, Get Answer, Expert's Help, Bovine spongiform encephalopathy Discussions

Write discussion on Bovine spongiform encephalopathy
Your posts are moderated
Related Questions
Equine infectious anaemia Equine infectious anemia (EIA), an acute or chronic viral disease of the equines, shows intermittent fever, loss of weight, depression, progressive w

Q. What is Osseointegration in macroscopic biomechanical? A fixture is osseointegrated if there is no progressive relative motion between the fixture and surrounding living bon

Receptors are sense organs that receive stimuli. On the basis of their location in body receptors are of following types - 1 .       Extero receptor - Located at or near t

Q. What are cerebrovascular accidents? The Cerebrovascular accident (CVA), as well known as stroke, is the generic name given to infarction (tissue and cellular death by hypoxi

GER M LAYER THEORY - Proposed by Pander, studied chick embryo development. Coined the term ectoderm, mesoderm & endoderm.

Non-Conventional Feed Resources There are many non-traditional or non-conventional materials which are available in abundance and can form potential source of feedstuffs for f

What are enzyme cofactors? Some enzymes require other associated molecules to work. These molecules are known as enzyme cofactors and they can be, for example, organic ions lik

Characteristics of Soil Profile  The profile characteristics studied in the field consist of locating the soil hor izons (based on its colour description that includes the  col

What proportion of children with Down syndrome do you expect when women with down syndrome have children with men who have 46 chromosomes? Justify answer

Skin The skin or integument is the outer covering of the body and have appendages i.e. nails and hairs. The outer layer of skin is known as epidermis; the inner layer is dermis