Bovine spongiform encephalopathy, Biology

Bovine spongiform encephalopathy

The bovine transmissible spongiform encephalopathy (BSE), known as 'mad cow disease'-first noticed in Great Britain in 1986, is similar to scrapie in sheep and Creustfeld Jacob syndrome (CJD) in man, chronic wasting disease of captive mule deer and rocky mountain elk and transmissible encephalopathies in mink. It has been reported from Northern Ireland, the Republic of Ireland, Oman, Switzerland, France, Germany and a few other European countries. There is no report of BSE in India so far although doubtful cases of CJD in human beings have been reported. The causative agent is structurally different from a virus in that it contains protein (PrP) which is a transformed naturally occurring protein constituent of neurons that is encoded by a single chromosomal gene and devoid of nucleic acid. This agent measures 30-50 nm and is extremely resistant to inactivation by heating, UV-irradiation and many chemicals. BSE is classified as Prion disease.


Epidemiology: The disease in cattle occurred as a result of feeding them with ruminant protein supplements in meat and bone-meal derived from scrapie-affected sheep.


Symptoms:
It is difficult to diagnose the disease on the basis of clinical signs since such signs are not quite spectacular. Histopathological and histochemical studies, electron microscopy and biochemical analysis for detection of prion protein are presently available for laboratory confirmation of the disease.Prevention, control and treatment: Identification and slaughtering of positive and suspected cases are the only means of control measures available at present

Posted Date: 9/18/2012 6:53:01 AM | Location : United States







Related Discussions:- Bovine spongiform encephalopathy, Assignment Help, Ask Question on Bovine spongiform encephalopathy, Get Answer, Expert's Help, Bovine spongiform encephalopathy Discussions

Write discussion on Bovine spongiform encephalopathy
Your posts are moderated
Related Questions
HACCP Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4


How is oil droplet different from micelles? Also describe the chemical make-up of each.

Q. Which is the part of the human visual system where the receptors that sense light, i.e., the photoreceptor cells, are located? How do those cells work? The photoreceptor cel

Q. Explain Natural History of Mitral Stenosis ? Untreated, mitral stenosis is a serious disease with observed 10-year mortality of 70-80 per cent in sy

What are the Haversian canals and the Volkmann's canals of the bones? Is the osseous tissue vascularized? The Haversian canals are longitudinal canals show in the osseous tissu

Q. Can you explain about Diagnostic coronary angiography? Diagnostic coronary angiography has become one of the primary components of cardiac catheterization. In a coronary ang

Define the term Underweight? Just as overweight is the result of a positive energy balance irrespective of the etiology, underweight results when the energy balance is negative

What do enzymes do, and how? How is enzyme activity regulated in cells? How do ATPases u se ATP to make reactions go?

Ernst Mayr, for whom, species and species problem have been the main concern of research, points out that speciation, the multiplication of species, that is division of one parent