Bovine leukemia, Biology

Bovine leukemia

Bovine leukemia, also known as bovine lymphosarcoma or leucosis, is a lymphoproliferative neoplastic disease of bovines. The virus belongs to genus Deltaretrovirus in the family Retroviridae. Oncogenesis depends on the integration of bovine proviral v-onc gene into cellular DNA. Transmission of Bovine leukemia virus occurs primarily by the transfer of lymphocytes between animals. The virus can be transmitted to the fetus but usually less than 40% calves born to infected dams are infected at birth.

Clinical signs: The symptoms of this disease are persistent lymphocytosis, leukemia and or lymphosarcoma in cattle. The lymphoid tumors are seen in lymph nodes, abomasums, heart, spleen, kidneys, uterus, spinal meninges, and brain.

Diagnosis: Antibodies to bovine leukemia virus antigens are demonstrated by immunodiffusion, radioimmunoassay, enzyme immunoassay, syncytium-inhibtion assay and complement-fixation test. The diagnosis is aided by the hematologic observations including lymphocytosis and the presence of immature lymphocytes. Electron microscopy, infectivity assay in cell-culture systems and sero-epidemiological observations provide a confirmatory diagnosis.

Prevention and control: Identification of the affected animals by serological testing followed by culling is the only available method of controlling this disease.

Posted Date: 9/18/2012 8:15:30 AM | Location : United States







Related Discussions:- Bovine leukemia, Assignment Help, Ask Question on Bovine leukemia, Get Answer, Expert's Help, Bovine leukemia Discussions

Write discussion on Bovine leukemia
Your posts are moderated
Related Questions
Barbiturate, Sedative, Hypnotic or Anxiolytic Intoxication and Withdrawal: This Emergencies related  to  substance abuse may be acute  or chronic. The patient may come  to  th

Q. What is the pineal gland? The pineal gland also known as epiphysis or pineal body is situated centrally in the head. It secretes the hormone melatonin. A hormone produced at

What is the genetic code? Genetic code is the key for the conversion of DNA nucleotide sequences (and therefore RNA nucleotide sequences) into amino acids sequences that will c

A glycosidic bond would be present in: Select one: a. acetone. b. methyl-alpha-D-glucose. c. 2-deoxy-beta-D-ribose. d. glucose-6-phosphate. e. fructose-1, 6-bisph

Compared to platyhelminthes which physiological problem have the cylindrical body of nematodes brought? How was that problem solved? The cylindrical shape of nematodes made imp

GAS T RUL A TIO N - Morphogenic movements are occured. 3 germinal layers are formed. Ectoderm, endoderm & mesoderm. Endoderm is formed first. Mesoderm is formed in the

Q. What are the two major morphological patterns of cnidarians? Concerning locomotion how do these forms differentiate from each other? Morphologically, cnidarians classify as

Define characteristics of prebiotics? Characteristics of prebiotics Are non-digestible dietary/food ingredients Are not hydrolyzed/absorbed in the upper GIT, reach

Pulmonary edema is life-threatening condition and therefore, treated as a medical emergency. As is the case with chronic stable heart failure, identification and correction of any

What is enzyme kinetics The study of the rate at which an enzyme works is called enzyme kinetics.