Why to outline some general mechanisms of toxicity

Assignment Help Biology
Reference no: EM1338417

1) Some theorists argue that there may be no clear threshold for effects such as carcinogenesis & mutation. What arguments do you think they might put forward in support of this?

2) It is important to understand the physiological means by which toxic agents cross cellular membranes & enter the cells of human body. Define & describe both passive & active transport?

3) Definition of toxicology?

4) What do you understand by the term dose? How can you estimate it?

5) What do you understand by the term effect? How is it measured?

6) Using examples distinguish between local and systemic and acute and chronic effects?

7) What do you understand by the term dose - effect and dose - response relations?

8) What is the impact on this relationship if there is more than one effect of a chemical?

9) What do you understand by the term 'threshold of effect'?

10) Define the terms toxico - kinetics and toxico - dynamics?

11) What factors influence chemical:

- Absorption
- Distribution and deposition
- Biotransformation
- Accumulation and elimination?

12) What do you understand by the term biological half time?

13) What is the significance, when setting threshold for adverse effects, of the fact that, broadly speaking, solid particulates have much longer biological half times than gases and vapours?

14) Briefly, what is the major underlying difference in body handling of a chemical between one and two compartment models of distribution and elimination?

15) Outline some general mechanisms of toxicity?

16) Describe a range of short and long-term toxicity testing methods?

17) Discuss the limitations of animal testing methods in the evaluation of human toxic potential of chemicals?

18) Outline a strategy for testing for carcinogenicity of industrial chemicals

Reference no: EM1338417

Amount of food the carrying capacity of the aquarium

A girl notices that her guppies reproduces most when herfish tank water is slighty alkaline. they stop reproducing if thewater becomes acidic or if the water becomes too alk

What are the absolute, average, and relative fitness

What advantages do the O-Scale System and the Canadian Physical Activity, Fitness and Lifestyle Approach-Health Body Composition Assessment procedure has in evaluation to perc

What is the market rate of return

Southern Gas recently paid a $2.75 annual dividend on its common stock. This dividend increases at an average rate of 4% per year. The stock is currently selling for $27.50

Illustrate the effecs of tonicity in redblood cells

The plasma membrane isa dynamic structure with bits continually being added and lost. Descibe how this occurs. Explain and illustrate the effecs of tonicity in redblood cells.

Differences between b and t-cell antigen receptors

In a concise table/chart compare the significant similarities, differences, cells, functions of the "Innate" and "Adaptive Immune Response. Describe the similarities and the

Basic theory of biological evolution

We are able to produce human insulin in bacteria by inserting the gene into bacteria. What is the basic theory of biological evolution and what evidence is there to support th

Definition of all three ethics morals and values

Definition of all three Ethics, Morals and Values and discuss the 3 concepts, and then discuss how they can influence an individual in a professional context. Please answ

Contrast health promotion and risk reduction

Compare and contrast health promotion and risk reduction as it would apply to a person with a chronic illness as opposed to a "healthy" person. Describe the healthcare appro

Reviews

Write a Review

 
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd