Which one is a protease inhibitor

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Reference no: EM13882717

1) Which one is a protease inhibitor ?

a) DDT       b)  Thiourea       c)  PMSF       d)  SDS

2) A non specific protease is ?

a) Pronase      b)  Trypsin       c)  Chymotrypsin        d)  Glu-C

3) The Tandem mass analyzer not used in ESI source is ?

a) Triple quadrupole   b)  Ion trap   c)  Fourier Transform Ion Cyclotron Resonance MS   d)  TOF

4) Which is not a physical Map?

a) Chromosomal map      b)  Radiation Hybrid map      c)  Linkage map      d)  Sequence map

5) Gene finding or prediction is an important application of ?

a) Functional genomics    b)  Structural genomics    c)  Comparative genomics    d)  Proteomics

6) Sanger’s dideoxy nucleotide method is also called ?

a) Maxam gilbert method  b)SAGE  c)Dye terminator sequencing  d)Chain termination method   

7) Microarray technology evolved from ?

a) Western blotting    b)  Southern blotting    c)  Northern blotting    d)  SDS – PAGE ?

8) Whole genome shotgun sequencing was done in ?

a) Institute for Genomic Research (TIGR)

b) European Bioinformatics Institute (EBI)

c) DOE-Joint Genome Institute

d) National Center for Biotechnology Information (NCBI) 

9) The initiation of Human genome project took place in ?

a) 1990       b)  1980       c)  1947       d)  1981

10) 2’,3’ – dideoxynucleotide triphosphates (ddNTPs ) molecules differ from deoxynucleotides by having a H atom attached  at which position to the carbon rather than an OH group ?

a) 2’       b)  2’, 3’       c)  3’       d)  None

11) The program or algorithm that can be used for peptide mass fingerprinting is ?

a) MS-tag       

b) Sequest       

c) Mascot       

d) SALSA

12) The Microarray technique also called Capture array ?

a) Reverse Phase protein Microarray

b) Functional protein Microarray

c) Analytical Microarray

d) DNA Microarray

13) The BAC to BAC method for sequencing the human genome is a ?

a) Map based method

b) Word method

c) Distance based method

d) Fragment based method

14) Tumor classification is done by which type of Microarray type ?

a) Expression analysis

b) Protein microarray 

c) DNA microarray

d) Comparative Genome Hybridization ( CGH )

15) All the steps are required for in-gel digestion except ?

a) Reduction and Alkylation

b) Destaining

c) Proteolytic cleavage

d) Ionization

16) Tandem Affinity Purification requires fusion of which tag to the target protein of interest ?

a) His tag       

b) Streptavidin tag       

c) Myc tag       

d) TAP tag

17) Cyanine dyes that are commonly used fluorophores with microarray are Cy ?

a) 3 , 5       b)  2 , 3       c)  5 , 6       4)  5 , 2 

18) The 20 KDa protein with 20 protons in a solution will have a m/z ratio of ?

a) 1001       b)  1002       c)  40       d)  20

19) Which method is used for analysis of gene expression pattern ?

a) Microarray 

b) SAGE      

c) Northern Blotting       

d) Maxam Gilbert method

20) The methods used by molecular biologists to produce snapshot of m-RNA in a sample of interest in the form of small tags is  ?

a) PAGE        

b) Reverse Transcription       

c) Microarray       

d) SAGE

Reference no: EM13882717

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