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Suppose you analyze three phenotypes in the common fruit fly Drosophila (A,B,D). The recessive alleles causing mutant phenotypes are represented by a,b, and d.
A test cross is performed between a trihybrid female with the wild type phenotype and a male with the three recessive phenotypes. The following progeny are obtained:
Class Phenotype Number1 AbD 732 Abd 1403 ABD 34 abD 7665 aBd 806 ABd 7567 abd 18 aBD 158Total 1000
A. Why do these data indicate genetic linkage of the three loci.
B. What is the order of the loci?
C. What are the alleles on each of the homologous chromosomes of the trihybrid female?
D. What are the recombination distances between each adjacent pair of loci?
E. What is the interference value for these data?
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describe the first step involved in replication of each genome. Your description can include a diagram and should cover.
Use chi-square test, test whether these two loci show independent assortment? How would you explain the frequency of the progeny genotypes?
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