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1. If normal cells were isolated many years ago and have been maintained in the lab through subculturing, would you expect this cell line now to be normal or transformed? why?
2. What is the difference between a homokaryon and a heterokaryon?
3. What role does PEG (polyethylene glycol) play in the formation of homokaryons and heterokaryons?
Mary has a genetically linked immunodeficiency. Unlike many such patients, who had recurrent infections with several gram-negative and/or gram-positive bacteria, Mary has only presented with infection with Neisseria meningitidis. Why is a phagocyt..
Compare the bone markings of the vertebrae and distinguish the differences between the cervical, thoracic, and lumbar vertebrae.
1. How many total base pairs are in all the mammalian genes? 2. What proportion (%) of the total genome does this represent? 3. What is the probability that a random mutation will occur in any given gene?
After performing a ligation reaction between the DNA fragments and cleaved vector, you analyze the products of the reaction by gel electrophoresis.
Why is cancer and cellular senescence a representation of two common cellular pathways associated with aging?
Those that live in tropical climates like the savannas of Africa are usually much smaller than the ones that live in arctic regions like Lapland.
Identify the 6-main skeletal muscles and tell how they function. There are so many of them, I couldn't find out which are the six majors.
An oligomeric protein has a molecular weight of 126000. A 820 mg sample was treated with an excess of 1-fluoro-2,4-dinitrobenzene until the reaction was finish.
Describe a microarray and how it works? Indicate what is fixed to a support and what is used to probe the microarray. How does a microarray differ from a Northern blot.
If NAD+ is an electron acceptor that becomes NADH and the NADH then donates a proton to ATPase, should not NADH now become NAD- since it lost it's proton but still has electron?
Explain how the cell regulates the transition from G1 phase to S phase. Describe the functions of the major regulatory proteins (which can include tumor suppressors).
If the epidermis is wounded (cut), epithelial cells must migrate out on the ECM of the dermis to cover the wounded area. Epithelial cells migrate through the use of transient focal adhesions.
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