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Q1. The venom of many cobras contains a potent neurotoxin that binds to ligand-gated Na+ channels, causing them to open. Unlike ACh, that binds to and after that rapidly unbinds from ligand-gated Na+ channels, the neurotoxin tends to stay bound to ligand-gated Na+ channels. How does this neurotoxin affect the nervous system's ability to stimulate skeletal muscle contraction? How does it affect the capability of skeletal muscle fibers to respond to stimulation?
Q2. Tay-Sachs disease is caused by loss-of-function mutations in a gene on chromosome 15 that encodes a lysosomal enzyme. It is inherited as an autosomal recessive condition. Among Ashkenazi Jews of Central European ancestry, about 1 in 3600 children is born with the disease. What fraction of individuals in this population are carriers?
Why may selfing be selected for in nature yet still be an ‘evolutionary dead end'. How many kilocalories must Janine eat each day to maintain her present body weight.
Assume that there are 63 different naturally occurring amino acids. If all 64 possible combinations of bases for a codon resulted in coding for 63 different amino acids and one stop codon, which of the next mutations would NOT be possible.
What caused the symptoms? What treatment has to have been administered in July? What treatment must be administered 2 years later.
Offer a model to explain how the F-box protein SLF and the S-RNase mediate self incompatibility. Be sure to account for the action of these proteins in compatible and incompatible interactions.
Glucose oxidase is an enzyme that can be used for measurements of glucose levels by combining this reaction with an oxygen probe.
At another locus, sepia eyes are inherited as an autosomal (non sex linked) recessive. The presence of the white eye phenotype (x superscript w x superscript w in females, x superscript y in males) masks sepia phenotype, so regardless of the sepia ge..
What type of compensation plan will you recommend? What are some of the problems you want to be aware of. Develop new coating methods and new applications of coating.
What phenotypic ratio would you get if you crossed a white mouse and a heterozygous brown mouse?
Explain three things that a paleontologist must do to plan a fossil hunting expedition so that he is likely to find evidence to reply a specific scientific question.
What veins are most likely involved? What pathologic changes have happened in these veins, and what is the most probable cause in this patient's case.
What part of the sewage treatment plant deals with insoluble and complex organic wastes? Which molecule contains more energy, X or Y.
What promotes exponential growth? What constrains population development.
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