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Thiol proteases are a widely distributed group of proteases with a mechanism somewhat similar to that of the serine proteases (the family of enzymes which includes chymotrypsin). The active site of one such protease, papain, contains a Cys and one other amino acid which along with the Cys facilitates catalysis.A. To which amino acid in the catalytic triad of chymotrypsin is the Cys analogous? B. What do you believe the other amino acid is most likely to be? Why?C. What sort of catalysis is the enzyme using the Cys to perform (proximity and orientation, general acid or base, etc.)?
Describe the direction of blood flow and the type of blood oxygenated or deoxygenated for each vessel in the pulmonary and systemic circuits.
What biological structure does the winding stairs in Jerome's apartment resemble and what components are represented by the "rails"?
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Chimpanzees have 24-pairs of chromosomes. Chimpanzee somatic cells contain DNA double helices.
Explain why have the angiotensin converting enzyme inhibitors replaced digoxin as the drug of choice in treatment of chronic heart failure?
Think about cells in adult mammals in which Barr bodies are observed. Indicate whether each of the following statements are true or false.
Diagram and explain the function(s) of the following biological molecules that comprise the plasma (cell) membrane: phospholipid bilayer, membrane proteins, carbohydrates.
Cleavage of DNA with restriction enzymes provides landmarks and sequence information. How frequently are specific sites found? How many sites are expected? Does this change if the DNA is circular.
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The intestinal stem cell sits exactly at position four in the crypt. What experiment was performed to find out it is the stem cell? At that position,
Explain why is glycine often found in loops of protein rather than in secondary structures such as beta-sheets and alpha helices?
Describe why people confined to wheelchairs as of paralyzed lower limbs have thin, weak bones in their thighs and legs.
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