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Q. HIV's genome of RNA includes code for reverse transcriptase (RT), an enzyme which acts early in infection to synthesize a DNA genome off of an RNA template. The HIV genome also codes for protease (PR), an enzyme that acts later in infection with cutting long viral polyproteins into smaller, functional proteins. Both RT and PR represent potential targets for antiretroviral drugs. Drugs known as nucleoside analogs (NA) act against RT, whereas drugs called protease inhibitors (PI) act against PR.
Which of these represents the treatment option that is most likely to avoid production of drug-resistant HIV (assuming no drug interactions or side effects)?
a. using a series of NAs, one at a time, and changed about once a week
b. using a single PI, but slowly increasing the dosage over the course of a week
c. using high doses of NA and a PI at the same time for a period not to exceed 1 day
d. using moderate doses of NA and of two different PI's at the same time for numerous months
How many stamens and pistils are in a shsta daisy "leucanthemum x superbum" from the family Asteraceae?
Why do bacteria secrete proteins? Select one: a. It is a strict requirement for function and to manipulate their environment b. To manipulate their environment and breakdown host target cells c. To change the host cell into a different type of cel..
Explain how phosphate limiting conditions for photosynthesis.
Create a pure-breeding double-mutant apricot, blunt line and cross it with wild-type wasps. The F 1 is wild-type in appearance.
For an amino acid such as alanine, the major species in solution at pH 7 is the zwitterionic form. Suppose a pKa value of 8 for the amino group and a pKa value of three for the carboxylic acid.
Fluoxetine can also inhibit ATP synthase. Why might long-term use of fluoxetine be a concern?
Fructose is a ketohexose monosaccharide discovered in honey, fruits, and other sources. It is also added to some foods and drinks as a sweetener.
What is phenol red used for in tissue culture work and what does a yellow color change in phenol red indicate in a tissue culture specimen?
Starting with IMP draw the pathways for the synthesis of ATP and GTP. You must include the structure, name of metabolite, name of enzymes, etc.
A farmer wishes to use genetically-modified crop in order to reduce cost on pesticides. The resistance gene, R, that provides protection for the crops is dominant and only 30 percent of the crops survive if they lack this gene.
Suppose that the you are given two cultures, one of a speacies of gram-positive bacterium and one of a species of Mycobacterium.
Diagnosis of CML can be done using a Southern blot to detect the junction fragment. In early stages of CML most patients are heterozygous for the genome rearrangement,
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