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In class, we discussed how H146 of the β-chain of normal adult hemoglobin ends up in close proximity to D94 on the same chain when oxygen is delivered to the tissues. In hemoglobin Hiroshima, however, H146 on the β-chain has been changed to a D through mutation.
a) What effect, if any, does this mutation have on oxygen binding by hemoglobin Hiroshima, compared to normal hemoglobin? Explain. Hb Hiroshima will bind O2 easier. (You explain why).
b) What effect, if any, does this mutation have on the Bohr Effect of this mutant hemoglobin? Explain. This mutation will weaken the H+ portion of the Bohr effect, but will have no consequence on the CO2 portion of the Bohr Effect. (You explain why for both).
Here, you are asked to do an energetic yield analysis for the complete oxidation of Palmitic Acid as an example of a saturated fatty acid. As in the previous problem, assume a P/O ratio of 2.5 for NADH (i.e. 2.5 ATP's per NADH oxidized in oxidati..
a what percentage of cancer cases in the uk is not due to lifestyle factors?b the article states that in women cases of
what is acute and convalescent sera? If the titer of the convalescent serum is much grater than the acute serum, what does that indicated.
What lands and observations inspired Darwin to develop his theory of evolution? How does the concept of natural selection explain variations in species descended from a common ancestor?
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every year approximately 42000 cases of salmonellosis are recored in the united states. due to many milder cases are
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Male frogs give calls that attract female frogs to approach and mate. Researchers reviewed mating calls of closely related tree frogs in South America.
q1. a new food additive was developed whereby fat could not be absorbed by intestines and then into the blood stream.
The role of O2 in electron transport In mitochondrial electron transport, what is the direct role of O2? a)to provide the driving force for the synthesis of ATP from ADP and Pi b)to function as the final electron acceptor in the electron transport..
"The Chimeric intron, which has been demonstrated to significantly increase transgene expression, is included in a variety of the mammalian expression vectors" - Almond, By Brian. "Promega ENotes - Applications." Promega Corporation - Precision De..
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