Interaction between hiv attachment proteins

Assignment Help Biology
Reference no: EM1395067

Maraviroc is a drug designed to block the interaction between HIV attachment proteins and the host cell receptor protein CCR5, thus blocking the initial stages of viral infection. Although Maraviroc shows promise in clinical trials, one major concern is the long term physiological impact of blocking CCR5. Why is this a concern?

a) Long term blocking would cause the CCR5 protein to mutate and it would no longer be functional as a receptor.

b) Like all host cell receptor proteins, CCR5 has a normal role for the cell, and long term blocking by Maraviroc would also block this normal role

c)CCR5 cell receptors would habituate to the continued presence of Maraviroc and the drug would lose its effectiveness.

 

Reference no: EM1395067

Questions Cloud

Dna genomes versus with rna genomes : A fundamental difference between eukaryotic viruses with DNA genomes versus those with RNA genomes is. Most eukaryal DNA viruses replicate in the host cell nucleus while most eukaryal RNA viruses replicate in the cytoplasm.
Performing simple linear regression : There are four conditions/requirements that must be met in order to perform simple linear regression. For each of the conditions below, choose the technique that should be used to determine whether or not that the condition is met.
Calculate the theoretical yield of lithium nitride : Determine the pressure in a 14.6 L cylinder filled with 0.440mol of N2 gas at a temperature of 327K.
Calculate the debye lengths : Compute the number of gms of CoCl2 that would be needed to prepare the solutions:(a) 550 mL of a 1.75 M solution (b) 210 mL of a 0.0180 M solution.
Interaction between hiv attachment proteins : Maraviroc is a drug designed to block the interaction between HIV attachment proteins and the host cell receptor protein CCR5, thus blocking the initial stages of viral infection.
Write critical implications of climate change for business : Write down the critical implications of climate change for business? Suitable ethical and sustainability theories and concepts covered.
How many atoms of mercury will be reported : Compute the heat amount required to heat a 3.9kg gold bar from 28 degree Celsius to 68 degree Celsius. Given Specific heat capacity of gold = 0.128 J/g°C.
Evolutionary implications of two major strategies of egress : What are the evolutionary implications of the two major strategies of egress. Viruses that egress by lysis are less "successful" from an evolutionary perspective because they kill their host cells.
Population amount of paint per can : Must you assume that the population amount of paint per can is normally distributed here? Explain

Reviews

Write a Review

 

Biology Questions & Answers

  Ionic-covalent bonds and functions of specialized tissue

Describe the difference between the ionic and covalent bonds. Describe the functions of the three specialized tissues in plants.

  How nineteenth century naturalist influenced the development

The science of ecology has roots in many disciplines. Describe how nineteenth century naturalist influenced the development of ecology.

  Use a minimum of three different websites or books

Research global warming on Web and write the final report outlining the path for the U.S. to follow to address the issue of global warming. Include at least three proposals for the US to follow, plus use a minimum of three different websites or books..

  Role of hox genes in brain development

Describe b riefly the role of HOX genes in brain development. If a twenty-five year old woman using Accutane to treat acne discovers that she is pregnant, what concerns do you have for the embryo/fetus?

  Determine type of epistasis is operated

Mating between black rats of identical genotype produced offspring as follows: 14 cream colored, 47 black, and nineteen albino.

  Observations of gram stained bacteria

Suppose that you did observations of Gram stained bacteria at TM 400x and TM 1000x. Which set of observations most closely matched the expected results for cell morphology.

  Diagram of small section of the plasma membrane

Develop a labeled diagram of a small section of the plasma membrane and briefly describe its structure and function.

  Identify the genus of causative agent of infection

An ASU student came down with severe diarrhea and vomiting after spring break at Cancun, Mexico. Laboratory tests of stool samples from the patient confirmed a gram negative bacterial pathogen as the cause of infection.

  Pre mrna processing

What procedure ensures that pre-mRNA processing is co-transcriptional? Disucss ow are all three steps of processing sequentially controlled?

  Why is social clock an important consideration

Why is social clock an important consideration when understanding development. It is a useful tool for making comparisons across different generations to see if the hypothesized developmental course is valid.

  The yield coefficient based on glucose

What proportion of male children in a large family will finally develop baldness in a marriage where both husband and wife are heterozygotes with genotype HnHb?

  Define how prokaryotes and eukaryotes provide different

define how prokaryotes and eukaryotes provide different. What does each category tell you about evolution; pick one from an early era and one from today or recent times.

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd