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Q1. For this assignment you will be provided with 2 clinical research questions on sample size and one published paper to determine the power of the primary outcome measure reported in the study.
Q2. A survey is being planned to estimate the prevalence of secondary infertility amongst couples aged 20-45. The investigators expect the prevalence to be 10%, and would like to estimate it to within 5% of the true value (with 90% confidence). How many couples are required?
Q3. A previous small study was investigating the total cost of 10 specific items of fruits and vegetables which were sold in 3 supermarkets compared to that were sold in 3 local corner shops. On average the total cost of 10 specific items of fruits and vegetables which were sold in local corner shops was £5.50. It was suggested that the total cost of those fruits and vegetables which were sold in supermarkets was 50% cheaper than the local corner shops, with a common standard deviation of 1.65. Use the PS power calculator to find out how many supermarkets and local corner shops are required (assume equal group) , if we are going to conduct a similar study to investigate the difference in cost of this size, with 90% power and using a 1% significance level?Q4. Read the paper titled "Plasma Fetuin -A is associated with the Severity and Cognitive Impairment in Mild to moderate Alzheimer's Disease" Edward R. Smith, RaminNilforooshan et al. Journal of Alzheimer's disease, 2010.
Identify the primary outcome measure and calculate using PS-sample size program to determine the power of the primary outcome measure, stating clearly the measures that were used to arrive at the result. Use 0.05 as type I error for the calculation. Also comment on the value of the difference whether this was clinically relevant or not.
Dana and Cathy are playing tennis. The probability that Dana wins at least one out of two ames is 0.3. What is the probability that Dana wins at least one out of four?
question 1 find the mean and standard deviation of the number of cars that have more than 1 passenger among the 500
The concentration of glucose(mg/dl) for all samples was measured on one run of a spectrophotometer 1. give the statistical model and full explain each component.
Determine a 95% confidence interval for true mean cost to repair this type of car.
What is the approximate estimated bootstrap standard error of the median, What is the approximate bias of the median estimated from bootstrapping - What is the bootstrap t confidence interval for the median
Describe the types of probability -example of classical probability, empirical probability, or subjective probability.
At the .01 significance level, can the manufacturer conclude that the price reduction resulted in an increase in sales?
four automobiles have entered bubbas repair shop for various types of work ranging from a transmission overhaul to a
The length of a particular telemarketing phone call has an exponential distribution with a mean equal to 1.5 minutes. Find the probability that the length of a randomly selected call will be between 30 - 50 minutes and 1 minuter or longer.
graphical depiction of data histogram and ogive1. make a grouped frequency distributionusing 35000 - 39999 as the
Standard deviation of 8 hours. what percentage of the bulbs have lifetimes that lie within 1 standard deviation to either side of the mean?
a deck of ordinary cards is shu?ed and 13 cards are dealt. what is the probability that the last card dealt is an
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