Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Recall that B-cells from neonatal spleen and adult marrow are susceptible to tolerance induction via deletion or editing strategies we discussed in class. However, if only early B-cell differentiation stages are susceptible to tolerance induction, consider this potential problem: Memory responses and long-lived plasma cells contain somatically mutated antibodies, that were selected for higher affinity. These mutations occur during primary responses, yielding altered CDR's. Since the mutations occur in functionally "mature" B-cells, how is any autoreactivity generated by these mutations eliminated from the memory B-cell pool?
Outline an experiment to establish whether mature B-cells that are the immediate progenitors of memory cells transit a "second window" of tolerance susceptibility while undergoing somatic mutation during initial antigen challenge. Be sure to indicate:
• how you would identify/isolate arising memory clones or their progenitors;
• how you would assess tolerance susceptibility and/or induction
• what your control and comparison groups would be.• Describe the result you would expect it there is such a second window of tolerance susceptibility.
A standard curve of absorbance as a function of oxidized DPIP concentration in ug/ml gives the following equation for the trend line: Y=.5X. The reaction volume was 7ml.
Miguel has congestive heart failure due to a valvular deficiency. He has edema in his ankles and hands. His liver is swollen, and he has accumulated fluid in his abdomen.
A analyzer is studying the inheritance of scale color in a new species of guppy. Base your answer on ALL of the following data.
Discuss a binomial system of nomenclature and explain the important contributions microorganisms make in the earth's ecosystems.
Your answer should also state the probability that any child who is conceived from the mating described in your mating diagram will have the MCAD deficiency phenotype.
Albinism in humans is inherited as a simple recessive trait. For the following families, estimate the gentypes of the parents and offspring.
Is this an instance of a positive or negative feedback mechanisms? What is the initial stimulus? What is the result.
Filling out two Punnett squares for a cross between a male with blood type B and a female with blood type AB. Build two Punnett squares and answer the following questions about them.
Suppose the diameer of a neutral helium atom is 1.40 x 10 to the second power pm. supposed that we could line up helium atoms side by side in contact with one another. How numerous atoms would it take to make the distance from end to end 9.00cm.
What is a lipase? Explain the difference in the osmium tetroxide and hematoxylin preparation treated slides with and with out lipase.
A batch animal cell culture has a productivity of 1.8 g/L*day, with a MUmax=0.5 days, a 10% inoculums and a turnaround time of 5 hours. If a continuous culture could operate at a dilution rate of 90% MUmax, explain what would be the productivity.
List and describe at least three cellular features of bacteria that could be targeted to inhibit or kill bacterial pathogen. Which is a significant flaw in this experimental set-up.
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +1-415-670-9521
Phone: +1-415-670-9521
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd