How would you attempt to inhibit glycolysis

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Imagine that a pharmaceutical company, specifically the research and development division, just hired you. Your first assignment consists of developing a new anticancer drug to control the high rates of glycolysis in tumor cells. Your company wants to target an enzyme different to hexokinase II, because they want to get ahead of competition (hexokinase inhibitors are popular drugs). What glycolytic enzyme (s) would target? Why? If you are not successful targeting glycolytic enzymes, how would you attempt to inhibit glycolysis? Provide at least one example to support your answer.

Reference no: EM13156607

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