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Signal transduction and cell cycle regulation intersect in a discussion of tumor formation. Pick one signal transduction pathway we have discussed. Describe the steps involved and how the pathway leads to cell cycle activation. Discuss three potential mutations of proteins along this pathway that could lead to tumor formation. Indicate whether such mutations would be expected to be gain of function or loss of function.
Write down an equation for the complete oxidation of glucose. What does this imply about the volume changes you would view if you simply sealed the pea seeds in a flask.
Determine how much in mL of .5 M NaOH total can you add to the solution in question 4 and still have a good buffer also Extimate the pH of a 0.05 M solution of TRIS acid (pKa=8.3)?
Calculate the Ki for a competitive inhibitor (I) form the following data by Dixon Plot.
leucine has two dissociable protons: one with pKa of 2.3, the other with a pKa of 9.7. Sketch a properly labeled titration curve for leucine titrated with NaOH; indicate where the pH = pK and the region(s) in which buffering occurs. Draw which str..
Illustrate the main types of faults and corresponding directions of stress. Differentiate between fault and joint. How does the stress differ between the two? Of what importance are these fractures to other geological processes.
Describe 6 functions that antibodies can perform (more than one isotype can perform many of these functions).
In snapdragons, the the genes A, B, C, and D assort independently of one another. If an Aa Ba Cc Dd plant is crossed with an Aa bb cc Dd plant, what is the probability of obtaining a snapdragon plant that is phenotypically dominant for all four tr..
How is a Scathard plot generated, and what measure of the inter-molecular interaction is used to find this?What is the proteasome.
You have read the literature about a lab that has isolated a gene for red pigmentation from petunias. The gene sequence is available in the database. You are a tomato geneticist and you want to study this gene in tomatoes.
Thiol proteases are a widely distributed group of proteases with a mechanism somewhat similar to that of the serine proteases the family of enzymes which includes chymotrypsin.
Determine the positions of the restriction sites in the DNA sequence.
Assume there is a picture of a neuron coming from the spinal cord and synapsing with a muscle fiber. Start in the neuron. Explain the stimulation of the soma.
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