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Suppose that an investigator considers conducting a case-control study to evaluate the relationship between invasive epithelial ovarian cancer and the history of infertility (yes/no). It is estimated that the proportion of controls with a history of infertility is about 10% and the investigator wishes to detect a relative risk of 2.0 with a power of 80% using a two- sided level of significance of 0.05.
(a) Find the total sample size needed if the two groups, cases and controls, are designed to have the same size.
(b) Find the total sample size needed if the investigator likes to have the number of controls four times the number of cases.
(c) Find the number of cases needed if the design is 1:1 matched; matching criteria are various menstrual characteristics, exogenous estrogen use, and prior pelvic surgeries.
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How does hypothesis testing contribute to the scientific knowledge base? What is one example of a null hypothesis statement?
test the claim that the mean gpa of night students is smaller than the mean gpa of day students at the .05 significance
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In particular, you would like to determine whether the two populations have the same mean age. A sample of 37 infected patients has mean age of 27.9 years and a standard deviation of 5.6 years; a sample of 19 patients who are not infected has mea..
the makers of compute-all know that in the past 40 of their sales were from people under 30 years old 45 of their sales
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