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A microsatellite marker has been found to be linked to a rare autosomal dominant disease in humans and can therefore be used to follow inheritance of the disease allele. The reliability of this microsatellite marker as a predictor of the disease is related to the map distance between the marker and the gene causing the disease. Your patient is a man affected with the disease (genotype Dd) who is heterozygous for the V1 and V2 alleles of the microsatellite marker, with his V1 allele on the same chromosome as his D allele and his V2 allele on the same chromosome as his d allele. His wife is V3V3 dd (V3 is another allele of the microsatellite marker). She is pregnant and is undergoing genetic testing by amniocentesis to predict whether the fetus will have the disease. The results demonstrate that the fetus has the V1 and V3 alleles of the microsatellite marker. What is the probability that the fetus has inherited the disease allele D if the distance between the D locus and the microsatellite marker locus is: (A) 0 map units? (B) 2 map units? (C) 50 map units? Please explain how to do it. I already have the answers for it.
The gene coding for the first six amino acids on the beta chain of normal hemoglobin A has the base pair sequence DNA GTA CCA GAC TGA GGA CTC
By some estimates there are only a couple of thousand great white sharks alive in the wild. Assume that in the frequency of LDH alleles in a sample of 200 adult sharks in a population off of Australia.
Determine which organelle found in plant cells is responsible for converting sunlight energy into the chemical energy found in sugar molecules?
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According to biochemical tests and oxygen usage, how would you identify and classify, respectively, the following microbes.
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5-different mutations were derived from base pair substitutions at a single codon. In this codon, the mutant alleles had arginine, leucine.
A 14-residue peptide, TRWVKVNGKWIKQA, in the context of a protein forms a hairpin, consisting of two anti-parallel ?-strands connected by a turn.
The most common therapy for warts is cryotherapy, in which liquid nitrogen is applied to the area of the wart every few weeks, freezing it for a few seconds until the wart falls off.
Red blood cells discovered in the plasma of mammals do not contain a nucleus. List all the possible benefits and limitations imposed on these cells by not having a nucleus.
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