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Explain why the "two-hit hypothesis" only applies to mutations in tumor suppressor genes and not to mutations in proto-oncogenes.
Explain the transport properties of the loop of Henle and describe the interactions between the ascending and descending limbs in the countercurrent multiplier system
Enzymes are typically required to catalyze reactions that would be very unlikely to occur on their own. Suppose that the activation energy, Ea, for the uncatalyzed cheese reaction at 20C is 18kcal/mol.
Describe the most probable pattern of inheritance for this condition. Fully explain your reasoning. Suppose that you can use laboratory mice as a model organism to research this disease. Outline sample genetic cross(es) that could be used to verif..
For each of amino acids, is the side chain hydrophobic, polar but uncharged, positively charged, or negatively charged at physiological pH?
Hiking in the deserts of New Mexico you encounter a strangely shaped, entirely smooth metallic rock. Oozing from the rock is a slime mold that you believe to be a new species never before seen (on earth). The mold fluoresces bright pink normally b..
Discuss why determinants for optimal microbial growth rates that are determined in pure cultures in the lab do often not correlate to those determinants in natural environments.
Ion concentrations have a impact on whether there is dissolution of minerals. Microorganisms can alter the charges on their cell surfaces to enhance these processes.
What issues need to be considered when planning an information systems project to increase data security?
Highly repetitive DNA is common in eukaryotic chromosomes, it does not code for proteins; in fact, it is probably never transcribed into RNA.
The restriction enzyme Scs1 cuts at a restriction site that is found only very rarely in dog genomes. One dog, Jimmy, has two restriction sites for this restriction enzyme in his genome. Another dog, Billy, has three restriction sites for this enz..
Which of the following statements is true about bacterial transformation? why?
A certain Drosophila protein-coding gene has one intron. If a large sample of null alleles of the gene are examined, will any of the mutant sites be expected in the
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