Explain what is the folding rate constant of this protein

Reference no: EM13662895

If Barnase is a two-state protein that is denatured in guanidium hydrochloride (GdnHCl). Barnase is 50% unfolded in 3 M GdnHCl, but 99% folded in 0.03 M GdnHCl. If 3 M solution of Barnase is diluted by a factor of 100 (that is to 0.03 M) it is observed to reach its new equilibrium in 12 minutes. Explain what is the folding rate constant of this protein.

Reference no: EM13662895

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