Effect on duration of sleep

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An investigational drug product was studied under sleep laboratory conditions to determine its effect on duration of sleep. A group of 16 patients willing to participate in the study were randomly assigned to one of two drug sequences; 8 were to receive the investigational drug in period 1 and an identical-appearing placebo in period 2, and the remaining 8 patients were to receive the treatment in the reverse order.

a. Identify the design.

b. Give a model for this design.

c. State the assumptions that might affect the appropriateness of this design.

Reference no: EM131029651

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