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The enzyme Bromelin is a cysteine protease from pineapple that utilizes a similar mechanism to serine proteases except the serine is replaced by a cysteine. Draw the mechanism of peptide hydrolysis by Bromelin. Start with the residues involved in catalysis and the substrate, and draw and label the structures for each of the following: 1) Michaelis complex 2) First tetrahedral transition state 3) acyl-enzyme intermediate (and first leaving group) 4) acyl-enzyme complex with attacking water molecule 5) second tetrahedral transition state 6) enzyme product complex.
In a germination experiment the germination rate and timing of wild radish (Raphanus raphanistrum) and crop radish (Raphanus sativus) were measured.
What will be the frequency of the sickle-cell allele in the next generation.
A dominant allele, A, causes yellow color in rats. The dominant allele of another independent gene, R, produces black coat color.
A young couple went to see a genetic counselor because each had a sibling affected with cystic fibrosis. (Cystic fibrosis is a recessive disease, and neither member of the couple nor any of their four parents is affected.)
What impact has society had (or still have) on the progress of scientific inquiry? How does ethical or moral values affect research and the sharing of scientific information?
Stenohaline osmoconformers such as sea anemones and sea stars, pH of arterial blood is slightly higher than that of venous blood because
The effective population sizes were recorded for population over five generations; 100, 120, 17, 40, 88. Estimate the harmonic mean of effective population size for this population?
Discuss and explain how ideas about stress immunization evolved into realization that maternal behavior actually plays an important role in mediating the effect of early stress, citing both animal and human research.
How would you explain to an untrained neighbor the process scientists use to change the genes of an organism to give it useful new traits?
Mark all key innovation of Spermatophyta over their ancestors (synapomophy).
Rabbits heterozygous for Pelger trait and exhibiting that phenotype are crossed. The offspring appear in a 2:1 ratio (Pelger : normal). Explain this strange ratio.
A population of collared lizards is fragmented into 3-glade populations through an aggressive anti-forest-fire campaign. At the "B" locus, there are only two alleles
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