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1) Describe principle behind various whole genome sequencing technologies. Describe application of one whole genome sequencing from literature for providing deeper insight into biological function.
2) You have isolated a novel transcription factor. How will you determine the genes regulated by transcription factor in the whole genome
3) How will you determine the transcription factor binding sites in the whole genome?
4) You have performed yeast two hybrid assay to identify proteins that interact with superman and identified a gene coding for kryptonite that interacts with superman. What experiments you will perform to demonstrate that the superman interacts with kryptonite in-vivo (inside nucleus in the cell)?
Give atleast two examples.
5) What is microRNA. Provide one example from literature how microRNA regulates mRNA.
Name two reasons why a gene tree might disagree with a species tree of the same taxa, even though both are evolutionarily correct.
Which of the statements regarding cellular respiration and photosynthesis is false? Select one: Cellular respiration and photosynthesis are chemically reverse reactions, but they use different pathways.
Spatially explicit model shows no evidence of admixture between Eurasians and Neanderthals
In 2006 paleontologists announced that fossils of Tiktaalik roseae, an important link between fish and tetrapods, had been discovered in freshwater sediments in the Canadian Arctic that were 375 million years old. How were geologists able to deter..
In mice, black eyes (B) are dominant over red eyes (b) and short ears (S) are dominant over having a long floppy ears (s). A black eyed, short eared mouse is crossed with a red eyed, long-eared mouse. The offspring has black eyes and long ears.
The recipe for 10x TBE buffer is 890 mM Tris, 890 mM boric acid, 20 mM EDTA. What is the concentration of 1x TBE buffer?
An electron transport system (ETS) of an organism contains all of the following components, Ubiquinone Manganese reductase Menaquinone NADH dehydrogenase
Describe gene duplication, homeobox genes, and retention of juvenile characters in the process of macroevolution. (Please be specific)
When mendel crossed yellow-seeded and green-seeded pea plants, all of offspring were yellow seeded. As he took these yellow-seeded plants and crossed then with green- seeded plants what genotypic ratio is expected.
The most common therapy for warts is cryotherapy, in which liquid nitrogen is applied to the area of the wart every few weeks, freezing it for a few seconds until the wart falls off.
Compare the spliceosome to the ribosome. What general features do they share in terms of their structure, their components, and their activity? How do they differ?
Compare the recipes of nutrient agar and MacConkey agar. If an organism can grow on both media,on which would you expect it to grow better?
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