Determine the coefficient of linkage disequilibrium
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Compute the solution of the given problem

Problem- In a very large random-mating population of mice, haplotype frequencies for the AB, Ab, aB, and ab genotypes are 0.1, 0.4, 0.3, and 0.2, respectively. Compute the coefficient of linkage disequilibrium D in this population. If Hardy-Weinberg assumptions are met and the recombination rate between these loci is R=0.2 per generation.

Part 1- what will the coefficient of linkage disequilibrium be one generation later? Five generations later?

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