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1 Describe the mechanisms by which input from GABAergic inhibitory neurons reduce action potential firing and neurotransmitter release. Why is the position of the inhibitory synapse on the neuron important in determining the effectiveness of the inhibitory stimuli?
2. Describe the different classes (ie., ionotropic and metabotropic) for BOTH the main EXCITATORY and INHIBITORY amino acid neurotransmitters of the central nervous system. Describe what molecule (ie., neurotransmitter) activates each of them, and once activated, what is the main cascade of events that follows.
3. Explain the difference between the whole-cell patch clamp technique versus the cell-attached patch clamp technique (also called "on-cell" patch) when recording electrically from a cell. How are these "patches" made and what kinds of questions can they answer?
4. Compare and contrast an "electrical" synapse with a chemical synapse. What is the difference in the size of the synaptic cleft for each type of synapse? How is the signal from the presynaptic cell transmitted to the postsynaptic cell? What are the major molecules involved?
Assume y ou are studying a gene, and its effects on skin cells. You want to find out if the protein made encoded by this gene binds to DNA in a particular place
The group of molecular biologists is trying to synthesize a new artificial compound to mimic the effects of a known hormone that influences sexual behaviour. They have turned to you for advice.
Assume you use phase contrast microscopy to observe a wet mount of a soil sample and a goo sample. In what ways are potential ET microbes similar to microbes previously characterized on earth?
How various of each possible phenotype. A locus in Australian Bearded Dragons is involved in the production of pigment. When heterozygous parents mate, 75% of the progeny are colored and the rest are albino.
Illustrate the process of diffusion. Name and explain the condition that exists when the diffusion of a particular substance is complete.
What is the benefit of a mouse liver cDNA library over a genomic library made from mouse liver. What is a lipid? Explain the different classes of lipids. What is a fatty acid? What makes acid saturated or unsaturated.
processes are harmed by the presence of oxygen are known.
make a discussion on the feasibility of using methylation analysis
What is the cellular tropism of HIV and does it change during the course of an infection? Which cellular receptors confer the preference for infection of certain cell-types?
Discuss how many different gametes are formed in a test cross when the cross examines one gene, two genes and three genes?
how data were collected during a study of the catalytic.
If a 100X solution is 1 M, what is the concentration of a 1X solution? Explain how you would prepare 100 mL of a 0.5 percent w/v agarose in 1X TAE buffer starting with a 20X TAE stock solution and solid agarose powder.
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