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1. Define sensitivity and specificity.
2. A cancer screening test is being applied in a population of 200 men who were also evaluated through the biopsy of tumor. 30 of the men were confirmed having cancer through biopsy. Out of these 30, 25 were also found to have cancer through the screening test. Screening test also found 15 cases to be having cancer but this was not confirmed by biopsy. Based on this information draw 2 x 2 table showing numbers in each of the 4 cells and compute sensitivity, specificity, Positive predictive value and Negative predictive values of the test for presence and absence of the disease.
3. Define positive predictive value (PPV) and negative predictive value (NPV).
4. An epidemiologist in Saudi Arabia wants to study the efficacy of iron supplementation for the prevention of HIV infection. He wants to make sure that only subjects who are free of HIV infection are enrolled in his trial. Based on the outcome of the test, he decides who could participate in his iron supplementation trail. For this purpose, it is very important that diagnostic test has high............... ........
one of the real challenges in medical practice around the world is that once clinical research is completed and
Radioactivity is a phenomenon of the spontaneous emission of A. protons (alpha particles) B. electrons (beta particles)
Determine the amino acid sequence of a peptide and You must supply the answer as the 3-letter amino acid sequence from N-terminus to C-terminus
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Tumor-promoting mutations are described as being either gain-of-function or loss-of function. Describe the effects of both classes of tumor-promoting mutations on the cell cycle and apoptosis.
What are some possible functions of MMR effectors (
Explain why is 5% (w/v) Sucrose solution hypotonic to the water plant cell, however a 5% (w/v) NaCI solution is hypertonic?
Determine which of the following statements about DNA replication is NOT correct? Starting with 15N15N DNA, and after TWO generations in the 14N medium, Escherichia coli cells will contain
What is the most accepted hypothesis on the origin of life on earth? How does it compare to the other main hypotheses?
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Draw the molecules involved in the condensation (formation of a peptide bond) between alanine and tyrosine. Draw the opposite hydrolysis reaction. (You need to draw the structures of alanine, tyrosine, and the peptide bond that forms.)
Identify the vector-borne disease
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