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1. Using temozolomide as a first new alkalating agent approved for treatment of malignant gliomas describe its mechanism of action, clinical benefits and major site effects. Compare to other compounds with similar mechanism of action.
2. Present the comparison of clinical benefits of the use of antineoplastic drugs. What criteria are used for selection and for monitoring of most commonly used antineoplastic drugs?
3. Briefly present the mechanism of action of inhibitors of intracellular signaling used for antineoplastic therapy?
4. Give your insights regarding present and future of biological therapies for cancer treatment.
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Assume that we have a population of three yellow phenotypes, three blue phenotypes, and three green phenotypes. A yellow phenotype then immigrates into the population. What are the genotype and allele frequencies after the immigration?
In a generalized transduction system using P1 phage, the done is pur+ nad + pdx- and the recipient is pur- nad- pdx+. The donor allele pur+ is initially selected after transduction.
Describe the process of coastal aging/smoothing. What forces drive the process? Name and describe 4 features that can form during this process.
Is habitat temperature reflected in the genomes? What is presumably connected to thermostability.
How many square miles of kelp are there in the world? Approximately how many tons of kelp are there in the world?
How are the endergonic reactions of the first phase of glycolysis coupled to the hydrolysis of ATP, whichis exergonic? How are the exergonic reactions of the second phaseof glycolysis coupled to the endergonic synthesis of ATP and NADH?
What can be intellectually stimulating or knowledgeable that can be gained from the study of Microbiology?
While Mexican hairless dogs are crossed with normally haired dogs, about half the pups are hairless and half have hair. While, though, two Mexican hairless dogs are mated, about a third of the pups produced hair, about two thirds are hairless and som..
How does bioremediation restore stability or clean up toxic pollutants and how does bioremediation control levels of pollution?
q. 1. which specific mycobacterium organism was ehrlich trying to stain while he developed the acid-fast stain?2. why
Discuss in detail how fungi get their nutrition. Relate this mode of nutrition to how a bed of fungal hyphae can so rapidly breakdown organic materials such as fallen leaves that are in contact with the soil.
q1. at the same time that you did the viable cell count of your bacterial culture in problem 10 you also counted the
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