Case study on the genetic code

Assignment Help Case Study
Reference no: EM131038569

Dangerously Thin:

A Case Study on the Genetic Code

1. Someone with a CYP2C9 genetic mutation would be at a much higher risk for overdosing on a prescribed drug like Warfarin because the enzyme needed to metabolize the drug is not functioning properly. The drug cannot be metabolized or broken down, causing it to become toxic.

2. DNA replication requires a messenger and a decoder carried out by the RNA. Messenger RNA (mRNA) carries the coded information where protein synthesis occurs, transfer RNA (tRNA) decodes mRNA's message for amino acid sequence in the polypeptide to be built. In Henry's case, the code is mutated and goes through the process of gene replication, which results in the wrong triplet code for the enzyme needed for breaking down the drugs. (Marieb, 2015)

3. Within each gene only one of the two strands of DNA, called the template strand is transcribed. The other complementary strand, referred to, as the non-template remains untranscribed. RNA polymerase reads the DNA template strand and produces the RNA transcript by adding nucleotides. (Purves, 2004)

4. a.) The sequence of the template strand would be AATGGCTCT.
b.) The DNA sequence code contains the triplet codes.
c.) After the sequence is transcribed the sequence would be UUACCGAGA. Thymine is replaced Uracil.
d.) Assuming that there is no start codon or termination signal three amino acids would be made.

5. a.) The nucleotide sequence on the template strand would be GAA.
b.) The mRNA condon that results after the triplet is transcribed as CUU.
c.) The anticodon of the tRNA molecule is GAA.
d.) The amino acid that would be carried by the tRNA molecule is Leucine.

6. a.) The template strand will now be ACA.
b.) The mRNA strand after being transcribed will now be UGU.
c.) The anticodon on the tRNA molecule that is complementary to the mRNA condon is ACA.
d.) The amino acid that would be carried by the tRNA molecule is Cytesine.

7. Henry's enzyme loses its function due to the change in amino acid. One mutated amino acid in the peptide changed the entire protein. Causing the structure to fold improperly, which in enzyme function, structure is a vital component. (Purves, 2004)

8. a.) Henry's first triple code ATT can be changed to ATC or ATA without resulting in a change in the amino acid, which is Isoleucine. Henry's second triplet code, CGT can be changed to CGU, CGA CGG to maintain the amino acid arginine. (Purves, 2004)
b.) There are five triplet codes that would not change the amino acid.
c.) The third position of the triplet code was changed for both DNA codes.
d.) From the pattern above I would conclude that if a mutation occurred in the first second position there would always be a change in the amino acid. If a change occurred on the third position it may or may not effect a change in the amino acid coding.

Marieb, E., & Joehn, K. (2015). Human Anatomy and Physiology. United States: Pearson
Education, Inc.

Purves W., Sadava, D., Orians, G., & Heller, C. (2004). Life: The Science of Biology. 7th Edition. United States: Sinauer and Freeman Education, Inc.

Reference no: EM131038569

Questions Cloud

Draw the structure of the carbocation : Remembering Markovnikov's rule (Section 13.6 in the textbook), draw the structure of the carbocation formed during the reaction of 2-methylpropene with {\rm HCl}.
Refer to the alligator food choice example : Refer to the alligator food choice example in Section 6.1.2. a. Using the model fit, estimate an odds ratio that describes the effect of length on primary food choice being either "invertebrate" or "other."
How much should you expect your profits to change : In response, she has proposed legislation that would award each existing firm 20 percent of a contract for 600 units at a contracted price of $100 per unit. If this legislation is passed, by how much should you expect your profits to change?
A model fit predicting preference for president : A model fit predicting preference for President (Democrat, Republican, Independent) using x = annual income (in $10,000 dollars) b. Find the range of x for which . c. State the prediction equation for πˆ I .
Case study on the genetic code : Someone with a CYP2C9 genetic mutation would be at a much higher risk for overdosing on a prescribed drug like Warfarin because the enzyme needed to metabolize the drug is not functioning properly.
Obtain the profit maximising level of output : If the market-clearing price is 6, obtain the profit maximising level of output.
The sole predictor for the probability of a satellite : The following are true-false questions. a. A model for a binary response has a continuous predictor. If the model truly holds, the deviance statistic for the model has an asymptotic chisquared distribution as the sample size increases.
Write a analysis for bernie sanders television advertisement : Write a rhetorical analysis for Bernie Sanders' television advertisement. Remember that the rhetorical analysis is a commentary on the effectiveness of the advertisement and not an evaluation of the candidate.
Which variable had the bigger percentage change : Compare non residential ixed investment with overall investment. Which variable had the bigger percentage change?

Reviews

Write a Review

 

Case Study Questions & Answers

  On the evening of march 12 about 36 hours after the initial

on the evening of march 12 about 36 hours after the initial call to the health department tdh staff conducted a matched

  Formally separate operations dbas from other dbas

Create a formal service-level agreement (SLA) between IS and end users for each database application. Formally separate operations DBAs from other DBAs, giving them different titles and possibly different managers.

  Describe the nature of tpgs advertising

Briefly describe the nature of TPG's advertising which caused ACCC to bring these proceedings and what statutory provisions did ACCC allege that TPG's advertising contravened.

  Discuss effects of your own enculturation or identification

Identify three premises from the Procon.org website that support your position and explain why you selected these specific reasons.

  Do you think that christie decision-making process is sound

Review Case Study in your Managing in the Public Sector text. If you were in Christie's position, what would you do? Be as detailed as possible. Explain your decision. Do you think that Christie's decision-making process is sound? Explain

  Explain management for quality and performance excellence

Explain Management for quality and performance excellence. The quality methodologies or practices that the company uses or plans to use to align performance excellence with its business objectives.

  What barriers she likely to encounter in completing project

What barriers is she likely to encounter in completing this project? What should she do between now and the next meeting?

  Case on overcoming political risk in crossborder transaction

Read the case on Overcoming Political Risk in Cross-Border Transactions - China's CNOOC Invests in Chesapeake Energy.

  Develop a report for tim outlining the factors

Develop a spreadsheet model that could be used to assist tim with retirement planning -  AS a feature of your spreadsheet model, build a data table to demonstrate the sensitivity of the age at which funds will be depleted to the retirement age and ..

  What steps should the president take next and why

What steps should the president take next? Why? What are the major legal and policy considerations that should guide the ultimate decision in this case?

  Case-who should take the fall

CASE-Who Should Take the Fall

  Moores on the signification of walls

What's that value? Share with the class 1) your experience with walls, 2) what expressions do you know that have to do with walls, 3) how can we put together (relate) Moore's article with that of Abbott?

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd