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Suppose you infect E. coli cells with two strains of T4 virus. One strain is minute (m), rapid lysis (r) and turbid (t); the other is wild-type for all three markers. The lytic products of this dual infection are plated on a lawn of E. coli and the morphology of the plaques are classified. The resulting 10, 342 plaques were distributed among eight phenotypes, as follows:
m r t 3467+ + + 3729m r + 853m + t 162m + + 520+ r t 474+ r + 172+ + t 965
You decide to repeat the exact same experiment as outlined above and this time you count and classify 25, 000 plaques? How many plaques would you expect to be wild-type for all three markers? (Hint: You will need to calculate the coefficient of coincidence for the cross above and apply that to your answer.)
How do both meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents? Be sure to talk about the two specific steps in meiosis that increase variability as well as process of fertilization.
Provide a basic toxicology report of the effects of PVC on a human, including possible carcinogens or neurotoxins?
The global community is plagued by increasing incidence of lung cancer, colorectal cancer, breast and pancreatic cancers, prostate cancer, leukemia, non-Hodgkin lymphoma, liver, ovarian and esophageal cancers.
Characteristics of a malignant state include: 1) Dysregulation of the cell cycle and 2) Inhibition of apoptosis. These mechanisms are also hallmarks of a many viral infections? Why are these characteristics also beneficial to many viruses? Explain ho..
Explore the role of the epigenome and/or other gene expression regulatory mechanisms in the development of cancer. Discuss in detail one possible epigenetic/post-transcriptional/post-translational target for cancer treatment, and identify the succes..
Diabetes and obesity are two metabolic diseases characterized by insulin resistance and a low grade inflammation. Seeking an inflammatory factor causative of the onset of insulin resistance.
What does this tell you about the physiological importance of hemoglobin's sigmoidal oxygenbinding curve. Which line represents the bag with the maximum initial concentration of sucrose.
how the specificity of each codon could be determined.
LDL particles have a higher percent content of cholesterol and cholesterol esters than VLDL particles. Describe the catabolism of the VLDL particles that occurs in the circulation and how this accounts for the increased content of cholesterol in t..
The cell walls if bacteria, fungi and plant cells and an extracellular matrix of animal cells are all external to the plasma membrane. Which is the characteristic of all these extracellular structures.
Environmental Carcinogens mutagens and other environmental carcinogens UV light organic solvents high energy radiation asbestos tobacco smoke others factors? What does UV light do to a cell.
Does this indicate that our original estimate of 350 individuals was too low or too high? Explain your answer in terms of the principles that underlie mark recapture method.
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