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You are studying what you suspect may be a new prion disease, and you conduct several experiments to test this idea. If truly caused by prions, which experiments do you predict will lead to infection of the subject? Select all that apply.
A. Experiment A: Brain tissue from an infected individual is transferred to the test subject.
B. Experiment B: Brain tissue from an infected individual is filtered with a Chamberland-Pasteur filter, then transferred to the test subject.
C. Experiment C: Brain tissue from an infected individual is treated with DNase and RNase, then transferred to the test subject.
D. Experiment D: Brain tissue from an infected individual is treated with proteinase, then transferred to the test subject.
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