>> Chemical Engineering
The batch fermentation of glucose to glutamic acid using Brevibacterium divaricate is described in detail in US patent 2,978,384. In Example I in the patent a 10.5 wt% glucose feed was fermented for 72 hours at 30 °C, giving 33.5 wt% glutamic acid yield on glucose. What annual production of glutamic acid can be achieved in a batch fermentation plant that has four 10,000 liter reactors? The reactors have jackets that can be used for steam heating or water cooling, but no internal coils.