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AChE contains a catalytic triad with the residues His, Glu, and Ser. The nerve agent sarin is an extremely potent inactivator of AChE. Sarin irreversibly inhibits AChE by covalently modifying the serine residue in the active site.
a. Diagram the expected arrangement of the amino acids in teh catalytic triad
b. Draw a mechanism for the covalent modification of AChE by sarin.
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Staying on theme with the Healthy Alternative Policy, I need assistance in taking one of the solutions from the last paper and creating recommendation document for the necessary stakeholders. The recommendation would Include the following while adh..
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