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1. Do analogue samples in depression research advance meaningfully our knowledge of depression and its treatment?
2. Are placebo trials in depression treatment studies ethical?
3. Are RCT designs in psychotherapy research essential and exclusively necessary to advance ESTs?
4. Should the Five Factor Model of Personality replace the current personality disorder system in DSM-5?
5. Should Watson's quantitative model of the mood and anxiety disorders replace the current system in DSM-5?
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