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Assume you have been examining a new drug that binds to PPAR? and produces its beneficial effect (increased insulin sensitivity). When you give this chemical to mice, you see kidney damage. Other PPAR? drugs did not lead to the same toxic effect and in a PPAR? knockout mouse you still see kidney damage. However, the type of damage that you see resembles drugs that affect another receptor called ROR. When ROR is knocked out in mice, you no longer see kidney damage, but you still see the beneficial effects. Which of the following is correct?
A) ROR is the ontarget receptor and PPAR? is the offtarget receptor
B) ROR is the offtarget receptor and PPAR? is the ontarget receptor
C) ROR activation is the doselimiting effect and PPAR? activation results in the chemicalmediated toxicity
D) ROR activation results in chemicalmediated toxicity and PPAR? activation results in the doselimiting effect
E) Other ROR drugs will result in increased insulin sensitivity
What does this show about the relation between voluntary and involuntary reflex movement. If the bacteriorhodopsin molecules were randomly oriented, would you expect ATP to be synthesized? Give details about the answers.
He was puzzled, combative, and he refuses to drink any water or any liquid. He lived on Oct. 7th, 1849. While said to the man's name, the student thought "Nevermore!" What was his diagnosis.
A 5.0 mL aliquot of a stock tryptophan solution was diluted by adding 95 mL of water. The absorbance of that diluted solution was measured at 280 nm as 0.055 absorbance units.
What are some of the unique circumstances of forensic genetic evidence.
Upon completion of genome sequencing projects, how do scientists usually go about asking how many genes there are in genome and where they are located.
Lakes would suffer a nutrient depletion in surface layers. Evaluate the sizes of the different digestive organs in the earthworm. Which organ is the main? How does its size make it well suited for its function.
Assume that you are increasing Downton wombats, carefully because they bite when teased. You notice that some of your wombats have white spots, whereas others have solid coats.
Yesterday, when Eric returned home from jogging, he was breathing heavily, sweating profusely, and complained that his legs ached and felt weak. He took a drink of Gatorade and took it easy until he could catch his breath.
find out the length of a DNA molecule in inches
Determine the possible DNA sequences that produced the four amino acids in the molecules
Rarely, hens reverse phenotypic (not chromosomal dew late in life and develop into sprem producing males. If such a male were to be mated to a normal female,what sex ratio will be expected among the offsrping.
define Why do we use 16s rDNA for sequencing
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