A review on advanced glycated end products (ages)

Assignment Help Biology
Reference no: EM13126 , Length: 30

AGEs are defined as the amine containing molecules which are formed through the nonenzymatic reaction between the reducing sugars and free amino groups of proteins, lipids and guanyl nucleotides in DNA. This report envelops the critical aspects related to AGEs under following heads:-

1.      Definition of AGEs: Advanced Glycated End Products

2.      Sources of AGEs

3.      Biology of Advanced glycation

4.      Metabolism of AGEs

5.      Receptors of AGEs

  • SR-A (Microphage Scavengers Receptors type I&II
  • OST-48 (Oligosaccharyl Transferese-4; AGE-R 1)
  • 80 KH Phosphoprotein (AGE- R 3)
  • Galectine 3 (AGE R-3)
  • LOX 1 (Lectine-Like Oxidized lower density Lipoprotein Receptor -1)
  • CD-36

6.      Antagonists of AGEs

7.      Retinopathy

8.      Neuropathy

9.      Nephropathy

10.  Atherosclerotic Diseases

11.  Measurement of AGEs

12.  References

Long-term studies validating both the specificity and sensitivity of this investigation, and its link to certain AGEs, remain to be confirmed. Thus, currently there is no evidence that the measurement of AGEs has any clinical use, and importantly, AGE measurements should not be considered a replacement for HbA1c as a marker of overall glycemic control.

Reference no: EM13126

Questions Cloud

A project report on study of statutory complainces : Statutory compliance and its immense knowledge are crucial to be understood in an organization. It contains all the forms, procedures and acts applicable in a company.
Hrp: recruitment and selection : Recruitment and Selection is the initial ladder of any Human Resource Planning process and contains an immense significance for any organisation.
Plastic as a soil stabilizer : Soil stabilization is the permanent physical and chemical alteration of soils to enhance their physical properties. Stabilization can increase the shear strength of a soil and control the shrink-swell properties.
A critical appraisal of npt: trends and challenges : This is a thesis, focused upon the Trends and Challenges of Nuclear Power Treaty. It is a very serious issue that need to be studied in depth.
A review on advanced glycated end products (ages) : This Project report elaborates a critical review of important elements attached to Advanced Glycated End Products (AGEs). It is very crucial to understand the process called Millard reaction.
Situation analysis of food security in new zealand : This paper aims to present, discuss and analyse factors that are causing low food security, the management, current and proposed solutions in New Zealand (NZ).
Personalized Cancer Therapy-A step forward : Cancer is the uncontrolled growth of abnormal cells in the body resulting in tumours that can be benign or malignant (cancerous cells). A proper treatment is necessary to fight with this serious disease.
Supporting Investment Promotion: ERNST & YOUNG : Ernst & young is currently providing support to various sectors. In this regards it was felt that if this report is able to document good practices currently being adopted or planned in ceramic sector.

Reviews

Write a Review

 

Biology Questions & Answers

  Immune response to infectious disease

It is a very curcial concept to understand how the immune response is mounted against viruses, bacteria, protozoans and helminthes. For an effective immune response, both innate and adaptive immunity should work together.

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd