+1-415-670-9189
info@expertsmind.com
A review on advanced glycated end products (ages)
Course:- Biology
Length: 30
Reference No.:- EM13126




Assignment Help
Expertsmind Rated 4.9 / 5 based on 47215 reviews.
Review Site
Assignment Help >> Biology

AGEs are defined as the amine containing molecules which are formed through the nonenzymatic reaction between the reducing sugars and free amino groups of proteins, lipids and guanyl nucleotides in DNA. This report envelops the critical aspects related to AGEs under following heads:-

1.      Definition of AGEs: Advanced Glycated End Products

2.      Sources of AGEs

3.      Biology of Advanced glycation

4.      Metabolism of AGEs

5.      Receptors of AGEs

  • SR-A (Microphage Scavengers Receptors type I&II
  • OST-48 (Oligosaccharyl Transferese-4; AGE-R 1)
  • 80 KH Phosphoprotein (AGE- R 3)
  • Galectine 3 (AGE R-3)
  • LOX 1 (Lectine-Like Oxidized lower density Lipoprotein Receptor -1)
  • CD-36

6.      Antagonists of AGEs

7.      Retinopathy

8.      Neuropathy

9.      Nephropathy

10.  Atherosclerotic Diseases

11.  Measurement of AGEs

12.  References

Long-term studies validating both the specificity and sensitivity of this investigation, and its link to certain AGEs, remain to be confirmed. Thus, currently there is no evidence that the measurement of AGEs has any clinical use, and importantly, AGE measurements should not be considered a replacement for HbA1c as a marker of overall glycemic control.




Put your comment
 
Minimize


Ask Question & Get Answers from Experts
Browse some more (Biology) Materials
What is t-cell mediated suppression? I have been trying to read about it and understand what it is.. but everything I read it doesn't really make sense to me.... and what me
Discuss somatic cell reprogramming with transcription factors and microRNA for cardiac tissue regeneration in animals. What is the treatment for scar tissue in soft tissue are
List the manifestations associated with adrenal medulla hyperfunction and explain how the alterations to normal physiology related to this disorder can cause them.
What are some pros and cons of the "EDC-free" lifestyle for individuals that do not suffer any known conditions from EDCs? (Does it benefit everyone's health, increase heal
In insulin mRNA, the protein coding sequence has 318 nucleotides. How many amino acids would be translated from this sequence? How many amino acids would be in the C peptide?
Describe the problems of larger bodies and the solutions that solved these problems but led to increased complexity. Consider advances of Porifera, Cnidaria, and Platyhelmin
If the experimental animals in the chamber were engaged in physical activity (such as running in a wheel), how do you think this would change results of the metabolism experim
You are studying a species of desert-dwelling fish that consists of only 2 populations, each located in a different canyon. Population A is consists of approximately 3000 br